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Preservation of RNA in a biological sample

  • US 7,056,673 B2
  • Filed: 04/15/2004
  • Issued: 06/06/2006
  • Est. Priority Date: 04/25/2003
  • Status: Expired due to Fees
First Claim
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1. A method of analyzing a biological sample comprising:

  • precipitating RNA in the biological sample by incubating the biological sample with an RNA preservative in an aqueous solution to yield a biological sample containing preserved RNA;

    histochemically staining the biological sample containing preserved RNA;

    histochemically analyzing the stained biological sample containing preserved RNA to identify specific cell populations; and

    analyzing mRNA expression patterns of the identified cells by a method comprising;

    in-situ hybridization;

    or isolating identified cells and subjecting the isolated cells to bioarray gene profiling.

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