Method and apparatus for self-diagnostic evaluation of nerve sensory latency

• US 7,058,438 B2
• Filed: 04/01/2003
• Issued: 06/06/2006
• Est. Priority Date: 11/02/2000
• Status: Expired due to Fees

• Current Assignee: Lawrence J. Grace, Richard J. Enroth
• Original Assignee: Lawrence J. Grace, Richard J. Enroth
• Inventors: Enroth, Richard J., Grace, Lawrence J.
• Primary Examiner(s): Bennett, Henry
• Assistant Examiner(s): PATEL, NIHIR B
• Application Number:
  US10/405,917
• Publication Number:
  US 20040024299A1
• Time in Patent Office: 1,162 Days
• Field of Search: 600/375, 600/372, 600/382, 600/384, 600/386, 600/546, 600/547, 600/554
• US Class Current: 600/375
• CPC Class Codes: A61B 5/05 Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves impedance plethysmography A61B5/0295; measuring movement of the entire body or parts thereof A61B5/11; detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof A61B5/24
• CPC Class Codes: A61B 5/1106 to assess neuromuscular blockade, e.g. to estimate depth of anaesthesia
• CPC Class Codes: A61B 5/4041 Evaluating nerves condition
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips

Abstract

A portable apparatus which allows a user to perform self-diagnostic evaluation of nerve sensory latency between a pair of epidermal locations proximal to nerve conduction paths. The device provides a simple and low-cost self-diagnostic apparatus which may be used for the detection and ongoing monitoring of sensory latency, such as sensory latency which is the result of carpal tunnel syndrome. The apparatus is powered by a single battery which provides power to all circuitry of the apparatus. Upon power activation, the device generates a series of high voltage stimulus pulses at an electrode in epidermal contact with the user/operator. The nerve response voltage is detected by a second electrode located along nerve pathway and the time delay between stimulus and response is displayed and periodically updated as each new response is detected.

Claims

1. An apparatus for self-diagnostic evaluation of nerve sensory latency, such as that which is symptomatic of carpal tunnel syndrome, comprising:

(a) a power source;

(b) a stimulator circuit configured for coupling to a first electrode at a first contact position on the skin of the user and for generating an electrical pulse from said power source at a selectable time;

(c) a sense circuit configured for coupling to a second electrode at a second contact position on the skin of the user and for detecting the nerve response associated with the electrical pulse generated by the stimulator circuit as it arrives proximal to said second contact position;

(d) a timer circuit configured for recording the time interval between the generation of the electrical pulse by the stimulator circuit and the arrival of the pulse response within the sense circuit; and

(e) a display circuit operatively coupled to said timer and configured for displaying the time interval as recorded by the timer circuit.

2. An apparatus as recited in claim 1, wherein said power source comprises a single battery.

3. An apparatus as recited in claim 1, wherein during the period of time that the power source is activated, the stimulator circuit generates a continuing series of electrical stimulus pulses.

4. An apparatus as recited in claim 1, further comprising voltage regulation circuitry coupled to said power source and configured for generating intermediate voltages for use within said circuits.

5. An apparatus as recited in claim 1, further comprising a peak detector within the sense circuit configured to detect a peak of an associated pulse response signal whereby noise immunity is improved over sensing performed with a fixed threshold.

6. An apparatus as recited in claim 1, wherein the stimulator circuit converts voltage provided by the power source to a sufficiently high voltage that said pulse can be properly coupled to the nerves within a nearby nerve pathway and registered by the sense circuit.

7. An apparatus as recited in claim 1, further comprising a charge pump circuit for incrementally converting the voltage provided by the power source to a high-voltage as stored on an output capacitor.

8. An apparatus as recited in claim 7, further comprising a transformer for converting the voltage which is stored on the output capacitor to a maximum peak voltage of around 200 volts.

9. An apparatus as recited in claim 1, wherein the timer circuit comprises a counter circuit configured to receive periodic pulses from an oscillator which modify a count value, the count value being loaded into the display in response to detecting the arrival of the stimulus pulse at the sensor circuit, and said counter being reset upon generation of a subsequent stimulus pulse.

10. An apparatus as recited in claim 9, wherein the display circuit comprises a liquid crystal display driven by an output stage of the counter circuit that also provides a phase signal utilized within the driver circuit for display segment driving.

11. An apparatus as recited in claim 9, wherein transition of a high-order intermediate output stage of the counter circuit provides a trigger signal which activates the stimulator circuit.

12. An apparatus as recited in claim 9, wherein an intermediate output stage of the counter circuit provides a second oscillator signal for the stimulator circuit, that in combination with the periodic pulses from the oscillator circuit provides the signal phases for operating a charge pump within the stimulator circuit so as to create a voltage of sufficient amplitude to properly drive the output of the stimulator upon being triggered.