Optical measuring system for diagnosing ear conditions

• US 7,058,441 B2
• Filed: 11/15/2001
• Issued: 06/06/2006
• Est. Priority Date: 11/16/2000
• Status: Expired due to Fees

• Current Assignee: Chameleon Medical Innovation Limited
• Original Assignee: Chameleon Medical Innovation Limited
• Inventors: Shahar, Menashe, Tenne, Meir
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US09/987,685
• Publication Number:
  US 20020087084A1
• Time in Patent Office: 1,664 Days
• Field of Search: 600473-478, 600/549, 600/200, 356/300, 356/302, 356/303, 356/326, 356/448
• US Class Current: 600/475
• CPC Class Codes: A61B 1/227 for ears, i.e. otoscopes
• CPC Class Codes: A61B 2560/0443 Modular apparatus
• CPC Class Codes: A61B 5/0075 by spectroscopy, i.e. measuring spectra, e.g. Raman spectroscopy, infrared absorption spectroscopy A61B5/0071 takes precedence
• CPC Class Codes: A61B 5/0084 for introduction into the body, e.g. by catheters A61B5/1459 takes precedence
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/7264 Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems neural networks per se G06N3/00; expert systems per se G06N5/00

Abstract

A system for detecting and diagnosing ear related conditions. The system includes a device capable of obtaining a spectrum of reflected light from an ear of a subject and a processing unit in connection with the device, which is capable of translating the obtained spectrum of reflected light to one or more output values related to the condition of the ear. The invention further provides a method for detecting and diagnosing ear related conditions including the steps of illuminating inside the ear; inserting a device to the ear canal capable of conveying at least one spectrum of reflected light from the ear to a processing unit; and activating the processing unit thereby translating at least one spectrum of reflected light provided at the time of activating to one or more output values related to the condition of the ear.

Claims

1. A system for use in detecting and diagnosing ear related conditions, the system comprising:

(a) a device capable of obtaining a spectrum of reflected light from an ear of a subject; and

(b) a processing unit in connection with said device which is capable of translating the obtained spectrum of reflected light to one or more output values related to the condition of the ear, the processing unit comprising a spectral analytical instrument in the form of a spectrometer, which receives said spectrum of reflected light and produces an analog signal indicative thereof, the processing unit being preprogrammed with certain models capable of analyzing the analog signal and converting it to at least one digital value presenting a spectrum vector indicative of a determined state of the ear, processing the spectrum vector by comparing to at least one predetermined reference value, and applying a classification model to the processed spectrum vector to thereby classify the determined state of the ear and generate output data indicative of one of the following ear conditions;

normal condition, serous otitis media condition, and otitis media condition.

2. The system of claim 1, wherein said spectrometer is sensitive to wavelengths of approximately between 400 nm to 1200 nm.

3. The system of claim 1, wherein said spectral analytical, instrument includes at least one filter.

4. The system of claim 1, wherein said processing unit further comprises a microprocessor interfaced with said converter.

5. The system of claim 4, wherein said microprocessor comprises an accessible memory.

6. The system of claim 1, wherein said processing unit comprises a display for displaying said one or more output values.

7. The system of claim 6, wherein said display includes an LCD display.

8. The system of claim 1, wherein said one or more output values indicate the health of the ear.

9. The system of claim 8, wherein said one or more output values indicate whether there is otitis media or serous otitis media.

10. The system of claim 9, wherein the statistical confidence of a decision relating to the existence of otitis media or serous otitis media is additionally indicated.

11. The system of claim 1, wherein said at least one reference value is at least one digital value resulting from diagnosing the other ear of said subject with said system.

12. The system of claim 1, wherein said at least one reference value is at least one digital value resulting from a diagnosis of a healthy ear with said system.

13. The system of claim 1, wherein said at least one reference value is a statistical range of values resulting from healthy ears.

14. The system of claim 1, wherein said at least one reference value is a statistical range of values resulting from ears with otitis media.

15. The system of claim 1, wherein said at least one reference value is a statistical range of values resulting from ears with serous otitis media.

16. The system of claim 1, wherein said processing unit further comprises an input unit including at least a numeric keyboard and an LCD display, for inputting information, and for further saving said information with said one or more output values in a file.

17. The system of claim 16, wherein said information includes at least one of the following:

user data and the side of said ear.

18. The system of claim 16, wherein said processing unit further comprises a clock for indicating the time and date of said one or more output values, and wherein the processing unit further saves said time and date with said one or more output values in said file.

19. The system of claim 16, wherein said processing unit is in communication with a personal computer.

20. The system of claim 1, wherein said system is incorporated into a single hand-held unit.

21. The system of claim 20, wherein the single hand-held unit is an otoscope.

22. The system of claim 1, wherein said device capable of obtaining a spectrum of reflected light is incorporated into an otoscope.

23. The system of claim 1, wherein the processing unit is configured to be connected to the internet.

24. The system of claim 1, wherein said processing unit is operable to translate at least one selected region of the obtained spectrum of the reflected light to said one or more output values related to the condition of the ear.

25. A system for use in detecting and diagnosing ear related conditions, the system comprising:

(a) a device capable of obtaining a spectrum of reflected light from an ear of a subject; and

(b) a processing unit in connection with said device which is capable of translating the obtained spectrum of reflected light to one or more output values related to the condition of the ear, the processing unit comprises a spectral analytical instrument in the form of a spectrometer for receiving said spectrum and producing an analog signal indicative thereof, the processing unit being preprogrammed with certain models capable of analyzing the analog signal and converting it to at least one digital value presenting a spectrum vector indicative of a determined state of the ear, processing the spectrum vector by comparing it to at least one predetermined reference value, and applying a classification model to the processed spectrum vector thereby classify the determined state of the ear and generate output data indicative of one of the following ear related conditions;

normal condition, serous otitis media condition, and otitis media condition, wherein said at least one digital value includes at least one digital value of a reflectance at wavelength of approximately 650–

700 nm, the processing unit being configured and operable for further comparing said value to a statistical reflectance at wavelength of approximately 650–

700 nm of a healthy ear thereby determining the redness degree of the tympanic membrane of said ear.

26. A system for use in detecting and diagnosing ear related conditions, the system comprising:

(a) a device capable of obtaining a spectrum of reflected light from an ear of a subject; and

(b) a processing unit in connection with said device which is capable of translating the obtained spectrum of reflected light to one or more output values related to the condition of the ear, the processing unit comprises a spectral analytical instrument in the form of a spectrometer for receiving said spectrum and producing an analog signal indicative thereof, the processing unit being preprogrammed with certain models capable of analyzing the analog signal and converting it to at least one digital value presenting a spectrum vector indicative of a determined state of the ear, processing the spectrum vector by comparing it to at least one predetermined reference value, and applying a classification model to the processed spectrum vector to thereby classify the determined state of the ear and generate output data indicative of one of the following ear related conditions;

normal condition, serous otitis media condition, and otitis media condition, wherein said at least one digital value includes a digital value of a reflectance of wavelength of approximately 962 nm, the processing unit being configured and operable for further comparing said value to a statistical reflectance at wavelength of approximately 962 nm of a healthy ear thereby determining the effusion degree in the middle ear.