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System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device

  • US 7,060,059 B2
  • Filed: 10/14/2003
  • Issued: 06/13/2006
  • Est. Priority Date: 10/11/2002
  • Status: Expired due to Term
First Claim
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1. A system for controlling the concentration of a substance in a patient, the system comprising:

  • a delivery device comprising at least one needle configured with a length sufficient to deliver a material to the intradermal compartment of said patient to result in at least one of rapid uptake of said material and rapid clearance of said material; and

    a controller, adapted to determine the concentration of said substance in the patient that occurs in response to said material delivered to the patient, and to provide an output that is adaptable for use to control the delivery device to control an amount of said material delivered to the patient based on the concentration of said substance.

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