Method and apparatuses for monitoring hemodynamic activities using an intracardiac impedance-derived parameter
First Claim
1. A cardiac pacemaker system comprising:
- (a) an implantable lead adaptable for sensing intracardiac electrical signals and delivering high and low energy pacing therapy, wherein the lead includes two or more electrodes at various distances from each other;
(b) a sensing module for detecting the intracardiac electrical signals;
(c) an impedance circuit for recording intracardia impedance signals;
(d) a microprocessor for computing an intracardiac impedance-derived parameter based on the impedance signals wherein the intracardiac impedance-derived parameter includes a ratio of a first value related to an area encompassed by a portion of an impedance waveform and a second value related to an area encompassed by a whole impedance waveform corresponding to a single cardiac cycle;
(e) a pacing controller for adjusting a pacing therapy delivered by the system according to the impedance-derived parameter;
(f) a pacing module for delivering pacing signals to the implantable lead according to the pacing therapy;
(g) a sensor for generating electrical signals associated with activity related to cardiac demand; and
(h) a second sensing module for receiving the activity related electrical signals from the sensor, wherein the pacing controller uses the intracardiac impedance-derived parameter to modify pacing therapies suggested by the sensor activity-related signals.
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Abstract
An intracardiac impedance-derived parameter, Half Cycle Activity (HCA) is used in sensing and controlling cardiac activities in implantable cardiac devices such as bradycardia pacemakers and cardioverter defibrillators. This impedance-derived parameter correlates closely with physical workload and at the same time provides hemodynamic feedback information. Thus, it allows a pacemaker system to implement accurately an increase in hemodynamically driven pacing rate, as well as to limit an inappropriate decrease of driven pacing rate advised by another sensor such as an accelerometer. In addition, it determines the maximum pacing rate for the pacemaker so as to prevent hemodynamic compromise. Therefore, the HCA parameter may be used to determine a Hemodynamic Upper Rate Limit and a Hemodynamic Lower Rate Limit, and thus define a Hemodynamic Pacing Range that is compatible with the range of physiological rate. This allows a closed-loop control of the pacing rate. In an implantable cardioverter defibrillator system, the hemodynamic tolerance of arrhythmias can also be assessed by using the HCA parameter to adjust therapy provided to a heart, such as antitachycardia pacing and/or cardioverting shocks.
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Citations
20 Claims
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1. A cardiac pacemaker system comprising:
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(a) an implantable lead adaptable for sensing intracardiac electrical signals and delivering high and low energy pacing therapy, wherein the lead includes two or more electrodes at various distances from each other;
(b) a sensing module for detecting the intracardiac electrical signals;
(c) an impedance circuit for recording intracardia impedance signals;
(d) a microprocessor for computing an intracardiac impedance-derived parameter based on the impedance signals wherein the intracardiac impedance-derived parameter includes a ratio of a first value related to an area encompassed by a portion of an impedance waveform and a second value related to an area encompassed by a whole impedance waveform corresponding to a single cardiac cycle;
(e) a pacing controller for adjusting a pacing therapy delivered by the system according to the impedance-derived parameter;
(f) a pacing module for delivering pacing signals to the implantable lead according to the pacing therapy;
(g) a sensor for generating electrical signals associated with activity related to cardiac demand; and
(h) a second sensing module for receiving the activity related electrical signals from the sensor, wherein the pacing controller uses the intracardiac impedance-derived parameter to modify pacing therapies suggested by the sensor activity-related signals. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. A method of monitoring hemodynamic efficacy of a patient'"'"'s heart rate comprising:
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computing an intracardiac impedance-derived parameter, wherein the intracardiac impedance-derived parameter includes a ratio of a first value related to an area encompassed by a portion of an impedance waveform and a second value related to an area encompassed by a whole impedance waveform corresponding to a single cardiac cycle, wherein the area encompassed by a portion of an impedance waveform and the area encompassed by the whole impedance waveform are determined relative to a baseline impedance value associated with respiration;
detecting a state of hemodynamic compromise based on the intracardiac impedance derived parameter when the rate is high; and
detecting that a hemodymanic demand is not being met when the rate is low. - View Dependent Claims (17, 18, 19, 20)
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Specification