Screws of cortical bone having a trailing end configured to cooperatively engage an implant

• US 7,063,701 B2
• Filed: 10/02/2001
• Issued: 06/20/2006
• Est. Priority Date: 05/05/1999
• Status: Expired due to Fees

• Current Assignee: Warsaw Orthopedic Incorporated (Medtronic Plc)
• Original Assignee: SDGI Holdings Incorporated (Medtronic Plc)
• Inventors: Michelson, Gary K.
• Primary Examiner(s): Reip, David O.
• Application Number:
  US09/970,241
• Publication Number:
  US 20020022843A1
• Time in Patent Office: 1,722 Days
• Field of Search: 606 62- 73, 606/61, 606/76, 606/77, 623/16.11, 623/17.11, 623/23.51, 623/23.58, 623/23.61, 623/26.63, 411/411, 411/417, 411/423, 411/416, 411/308, 411/904
• US Class Current: 606/307
• CPC Class Codes: A61B 17/7059 Cortical plates A61B17/7007, A61B17/7058 take precedence
• CPC Class Codes: A61B 17/8033 having indirect contact with screw heads, or having contact with screw heads maintained with the aid of additional components, e.g. nuts, wedges or head covers
• CPC Class Codes: A61B 17/8038 the additional component being inserted in the screw head
• CPC Class Codes: A61B 17/8042 the additional component being a cover over the screw head
• CPC Class Codes: A61B 17/8057 the interlocking form comprising a thread
• CPC Class Codes: A61B 17/8605 Heads, i.e. proximal ends projecting from bone
• CPC Class Codes: A61B 17/866 Material or manufacture
• CPC Class Codes: A61B 17/888 the driver bit acting on the central region of the screw head
• CPC Class Codes: A61B 2017/00004 (bio)absorbable, (bio)resorbable or resorptive
• CPC Class Codes: A61F 2/28 Bones joints A61F2/30
• CPC Class Codes: A61F 2/442 Intervertebral or spinal discs, e.g. resilient non-disc-shaped intervertebral inflatable pockets A61F2/441; non-disc-shaped intervertebral fusion implants A61F2/4455
• CPC Class Codes: A61F 2/4455 for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages intervertebral discs A61F2/442
• CPC Class Codes: A61F 2/4611 of spinal prostheses
• CPC Class Codes: A61F 2002/2839 Bone plugs or bone graft dowels
• CPC Class Codes: A61F 2002/30507 using a threaded locking member, e.g. a locking screw or a set screw
• CPC Class Codes: A61F 2002/30578 having apertures, e.g. for receiving fixation screws
• CPC Class Codes: A61F 2002/30774 internally-threaded
• CPC Class Codes: A61F 2002/30777 Oblong apertures
• CPC Class Codes: A61F 2002/30787 inclined obliquely with respect to each other
• CPC Class Codes: A61F 2002/30797 internally-threaded
• CPC Class Codes: A61F 2002/30904 : serrated profile, i.e. saw-toothed
• CPC Class Codes: A61F 2220/0025 : Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
• CPC Class Codes: A61F 2310/00359 : Bone or bony tissue
• CPC Class Codes: A61F 2310/00976 : Coating or prosthesis-covering structure made of proteins or of polypeptides, e.g. of bone morphogenic proteins BMP or of transforming growth factors TGF
• CPC Class Codes: Y10S 606/909 : Bone
• CPC Class Codes: Y10T 29/49947 : by applying separate fastener

Abstract

A screw formed of cortical bone for use in the human body with an implant having a screw hole for receiving at least a portion of a screw therethrough, includes a shaft with a thread along at least a portion of its length. The thread has an outer diameter dimensioned to pass through the screw hole in the implant. The trailing end of the screw is configured to cooperatively engage at least a portion of the screw hole of the implant so as to prevent the screw from linear motion along the mid-longitudinal axis of the shaft in a direction opposite to the direction of insertion when the screw is threaded through the screw hole to attach the implant to a bone portion of the human body. The screw is formed substantially of cortical bone of a single cortical thickness.

Claims

1. A screw formed of cortical bone for use in the human body with an implant having a screw hole for receiving at least a portion of a screw therethrough, said screw comprising:

a leading end, a trailing end apposite said leading end, and a shaft therebetween, said shaft having a mid-longitudinal axis and a length;

a thread extending from said shaft along at least a portion of its length, said thread having an outer diameter dimensioned to pass through the screw hole in the implant;

said trailing end being configured to cooperatively engage at least a portion of the screw hole of the implant so as to prevent said screw from linear motion along the mid-longitudinal axis of said shaft in a direction opposite to the direction of insertion when said screw is threaded through the screw hole to attach the implant to a bone portion of the human body; and

said screw being formed substantially of cortical bone of a single cortical thickness.

2. The screw of claim 1, further comprising an enlarged portion proximate said trailing end with a dimension transverse to the mid-longitudinal axis of said shaft greater than said outer diameter of said thread, said enlarged portion configured to prevent said trailing end from passing through the screw hole in the implant.

3. The screw of claim 2, wherein said enlarged portion forms a head.

4. The screw of claim 1, wherein said trailing end includes a second thread having a different thread pitch than said thread along said shaft.

5. The screw of claim 4, wherein the thread pitch of said second thread is similar to a metal screw pitch.

6. The screw of claim 4, wherein the thread pitch of said thread along said shaft is similar to a wood screw pitch.

7. The screw of claim 1, wherein the thread pitch of said thread along said shaft is similar to a wood screw pitch.

8. The screw of claim 1, wherein at least a portion of said trailing end is expandable.

9. The screw of claim 8, wherein at least a portion of said trailing end is divided into at least two members with an opening therebetween.

10. The screw of claim 9, further comprising an insert configured to fit into said opening of said trailing end and to move said at least two members apart when inserted into said opening.

11. The screw of claim 10, wherein said insert is configured to be inserted by linear advancement into said opening.

12. The screw of claim 11, wherein said insert has a cruciate shape and said opening has a corresponding cruciate shape.

13. The screw of claim 10, wherein said insert is configured to be inserted by rotational movement into said opening.

14. The screw of claim 13, wherein said insert is threaded.

15. The screw of claim 1, wherein at feast a portion of said trailing end is configured to cooperatively engage a driving instrument for insertion of said screw.

16. The screw of claim 15, wherein said trailing end includes a recess to cooperatively engage a driving instrument.

17. The screw of claim 16, wherein said recess is one of cruciate-shape and hex-shaped.

18. The screw of claim 15, wherein said trailing end includes a protrusion to cooperatively engage a driving instrument.

19. The screw of claim 18, wherein said protrusion has a hex-shaped perimeter.

20. The screw of claim 1, wherein said thread is sharper proximate said leading end than proximate said trailing end.

21. The screw of claim 1, wherein said thread has a V-shaped cross section with an apex and a base adjacent to said shaft, said base being substantially wider than said apex.

22. The screw of claim 1, wherein said thread has a peak as measured from said shaft, the peak being greater proximate said lading end than said trailing end.

23. The screw of claim 1, wherein said shaft has a root diameter that increases in the direction from said leading end to said trailing end.

24. The screw of claim 1, wherein said leading end forms a tip and said tip is fluted.

25. The screw of claim 1, wherein said cortical bone is obtained from a human.

26. The screw of claim 1, wherein said cortical bone is obtained from a generally intramembraneously formed cortical bone.

27. The screw of claim 26, wherein said cortical bone is obtained from a human skull.

28. The screw of claim 1, wherein said cortical bone is obtained from a large tubular bone of a human.

29. The screw of claim 28, wherein said cortical bone is from the diaphyseal region of said large tubular bone.

30. The screw of claim 28, wherein the tubular bone is a femur.

31. The screw of claim 1, further comprising a bioresorbable material other than cortical bone.

32. The screw of claim 31, wherein said material includes bioresorbable plastics.

33. The screw of claim 32, wherein said material includes at least one of glycolide polymers, lactide, capralactone, trimethylene carbonate, and dioxanone.

34. The screw of claim 1, wherein said screw comprises bone growth promoting material.

35. The screw of claim 34, wherein said bone growth promoting material is selected from one of bone morphogenetic protein, hydroxyapatite, and genes coding for the production of bone.

36. The screw of claim 1, wherein said screw is treated with a bone growth promoting substance.

37. The apparatus of claim 1, in combination with a bone growth promoting material.

38. The apparatus of claim 37, wherein said bone growth promoting material includes at least one of bone morphogenetic protein, mineralizing proteins, hydroxyapatite, and genetic material coding for the production of bone.

39. A screw formed of cortical bone for use in the human body with an implant having a screw hole for receiving at least a portion of a screw therethrough, said screw comprising:

a leading end, a trailing end opposite said leading end, and a shaft therebetween, said shaft having a mid-longitudinal axis arid a length;

a thread extending from said shaft along at least a portion of its length, said thread having an outer diameter dimensioned to pass through the screw hole in the implant;

said trailing end being configured to cooperatively engage at least a portion of the screw hole of the implant so as to prevent said screw from linear motion along the mid-longitudinal axis of said shaft in a direction opposite to the direction of insertion when said screw is threaded through the screw hole to attach the implant to a bone portion of the human body;

an enlarged portion proximate said trailing end with a dimension transverse to the mid-longitudinal axis of said shaft greater than said outer diameter of said thread, said enlarged portion configured to prevent said trailing end from passing through the screw hole in the implant, said enlarged portion forming a lip; and

said screw being formed substantially of cortical bone of a single cortical thickness.

40. The screw of claim 39, wherein said enlarged portion forms a head.

41. The screw of claim 39, wherein said trailing end includes a second thread having a different thread pitch than said thread along said shaft.

42. The screw of claim 41, wherein the thread pitch of said second thread is similar to a metal screw pitch.

43. The screw of claim 41, wherein the thread pitch of said thread along said shaft is similar to a wood screw pitch.

44. The screw of claim 39, wherein the thread pitch of said thread along said shaft is similar to a wood screw pitch.

45. The screw of claim 39, wherein at least a portion of said trailing end is expandable.

46. The screw of claim 45, wherein at least a portion of said trailing end is divided into at least two members with an opening therebetween.

47. The screw of claim 46, further comprising an insert configured to fit into said opening of said trailing end and to move said at least two members apart when inserted into said opening.

48. The screw of claim 47, wherein said insert is configured to be inserted by linear advancement into said opening.

49. The screw of claim 48, wherein said insert has a cruciate shape and said opening has a corresponding cruciate shape.

50. The screw of claim 47, wherein said insert is configured to be inserted by rotational movement into said opening.

51. The screw of claim 50, wherein said insert is threaded.

52. The screw of claim 39, wherein at least a portion of said trailing end is configured to cooperatively engage a driving instrument for insertion of said screw.

53. The screw of claim 52, wherein said trailing end includes a recess to cooperatively engage a driving instrument.

54. The screw of claim 53, wherein said recess is one of cruciate-shape and hex-shaped.

55. The screw of claim 52, wherein said trailing end includes a protrusion to cooperatively engage a driving instrument.

56. The screw of claim 55, wherein said protrusion has a hex-shaped perimeter.

57. The screw of claim 39, wherein said thread is sharper proximate said leading end than proximate said trailing end.

58. The screw of claim 39, wherein said thread has a V-shaped cross section with an apex and a base adjacent to said shaft, said base being substantially wider than said apex.

59. The screw of claim 39, wherein said thread has a peak as measured from said shaft, the peak being greater proximate said leading end than said trailing end.

60. The screw of claim 39, wherein said shaft has a root diameter that increases in the direction from said leading arid to said trailing end.

61. The screw of claim 39, wherein said leading end forms a tip and said tip is fluted.

62. The screw of claim 39, wherein said cortical bone is obtained from a human.

63. The screw of claim 39, wherein said cortical bone is obtained from a generally intramembraneously formed cortical bone.

64. The screw of claim 63, wherein said cortical bone is obtained from a human skull.

65. The screw of claim 39, wherein said conical bone is obtained from a large tubular bone of a human.

66. The screw of claim 65, wherein said cortical bone is from the diaphyseal region of said large tubular bone.

67. The screw of claim 65, wherein the tubular bone is a femur.

68. The screw of claim 39, further comprising a bioresorbable material other than cortical bone.

69. The screw of claim 68, wherein said material includes bioresorbable plastics.

70. The screw of claim 69, wherein said material includes at least one of glycolide polymers, lactide, capralactone, trimethylene carbonate, and dioxanone.

71. The screw of claim 39, wherein said screw comprises bone growth promoting material.

72. The screw of claim 71, wherein said bone growth promoting material is selected from one of bone morphogenetic protein, hydroxyapatite, and genes coding for the production of bone.

73. The screw of claim 39, wherein said screw is treated with a bone growth promoting substance.