Determined DNA sequences derived from a papillomavirus genome, their uses for in vitro diagnostic purposes and the production of antigenic compositions
First Claim
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1. A method for detecting the presence of human papillomavirus in a sample comprising:
- combining a test sample containing sample nucleic acids with a composition comprising at least one nucleotide sequence from human papillomavirus-33, wherein the human papillomavirus-33 is defined by the sequence as shown in FIG. 1a and FIG. 1b; and
identifying the presence of hybrids formed between said sample nucleic acids and said at least one nucleotide sequence from human papillomavirus-33.
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Abstract
The invention concerns DNA fragments derived from the genomic DNA of HPV-33. These fragments are selected from the group of fragments extending between the nucleotide extremities defined hereafter in relation to the nucleotide-numbering in FIGS. 1a and 1b respectively:
- 76–556
- 543–864
- 867–2811
- 2728–3808
- 3326–3575
- 3842–4079
- 4198–5611
- 5516–8091.
The invention also relates to the use of these fragments as probes for the detection of HPV in tissue cultures.
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Citations
12 Claims
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1. A method for detecting the presence of human papillomavirus in a sample comprising:
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combining a test sample containing sample nucleic acids with a composition comprising at least one nucleotide sequence from human papillomavirus-33, wherein the human papillomavirus-33 is defined by the sequence as shown in FIG. 1 a andFIG. 1 b; andidentifying the presence of hybrids formed between said sample nucleic acids and said at least one nucleotide sequence from human papillomavirus-33. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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