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System, method, and device for non-invasive body fluid sampling and analysis

  • US 7,066,884 B2
  • Filed: 03/16/2001
  • Issued: 06/27/2006
  • Est. Priority Date: 01/08/1998
  • Status: Expired due to Fees
First Claim
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1. A method for non-invasive body fluid sampling and analysis, comprising:

  • identifying an area of biological membrane having a permeability level;

    increasing the permeability level of the area of biological membrane by applying ultrasound having a frequency range of from about 10 kHz to about 500 kHz to the area of biological membrane;

    contacting the area of biological membrane with a receiver;

    extracting at least one analyte of the body fluid through and out of the area of biological membrane and into the receiver;

    providing an external force to enhance the extraction of the at least one analyte;

    continuously analyzing the at least one analyte; and

    providing the results of the step of continuously analyzing the at least one analyte.

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