Method and apparatus for gauging severity of myocardial ischemic episodes

• US 7,066,891 B2
• Filed: 12/20/2002
• Issued: 06/27/2006
• Est. Priority Date: 12/20/2002
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Moore, Thomas R., Lu, Steven N., Stadler, Robert W., King, Gary W.
• Primary Examiner(s): Manuel, George
• Assistant Examiner(s): KRAMER, NICOLE R
• Application Number:
  US10/325,076
• Publication Number:
  US 20040122478A1
• Time in Patent Office: 1,285 Days
• Field of Search: 600/508, 607/17
• US Class Current: 600/508
• CPC Class Codes: A61B 5/349 Detecting specific parameters of the electrocardiograph cycle
• CPC Class Codes: A61B 5/358 Detecting ST segments
• CPC Class Codes: A61N 1/3629 in combination with non-electric therapy

Abstract

An implantable medical device (IMD) for gauging the severity of ischemia in a patient'"'"'s heart includes a data collection module configured to receive data about the patient'"'"'s heart, a data processing module configured to process the data to identify an episode of ischemia in the patient and to determine if the episode is stable or unstable, and a reporting module configured to provide an alarm to the patient if the episode is unstable. A method executable by an implantable medical device to detect ischemia in a human heart suitably includes the steps of receiving data about the heart at the implantable medical device, processing the data within the implantable medical device to determine the severity of ischemia, and providing a response from the implantable medical device to the patient if ischemia is indicated.

Claims

1. A method executable by an implantable medical device (IMD) to detect ischemia in a patient'"'"'s heart, the method comprising the steps of:

receiving data about at least one physiologic parameter related to the severity of an ischemic episode of a patient'"'"'s heart via an IMD;

processing the data within the IMD to determine the severity of the ischemic episode, wherein said severity is deemed higher according to preselected criteria;

in the event that the severity of the ischemic episode exceeds a present value of a variable threshold, providing an alert signal from the IMD to the patient, wherein the alert signal is determined as a function of the severity of the ischemic episode; and

modulating a palliative ischemia therapy based on the relative severity of the ischemic episode

wherein the processing step comprises the steps of determining whether the ischemic episode can be classified as a stable ischemic episode or an unstable ischemic episode.

2. The method of claim 1 wherein the receiving step comprises receiving electrocardiogram (ECG) data.

3. The method of claim 2 wherein the processing step comprises interpreting an ST segment of the ECG data.

4. The method of claim 3 wherein the processing step further comprises interpreting accelerometer data.

5. The method of claim 1 further comprising:

gathering feedback data about the heart during a temporal interval subsequent to the time the data was received and while the alert signal is being provided, and

adjusting the alert signal as a function of the feedback data.

6. The method of claim 1 wherein modulating the palliative ischemia therapy comprises providing a dose of an anti-ischemia medication dispensed from one of the IMD and an implantable drug-delivery device.

7. The method of claim 1 wherein the palliative therapy comprises providing an electrical signal in electrical communication with excitable tissue of the heart.

8. The method of claim 1 wherein the palliative therapy comprises a neurological stimualtion therpy.

9. The method of claim 1 further comprising the step of storing results data in a memory if the ischemic episode is classified as a stable ischemic episode.

10. A method of gauging the severity of ischemia in a patient'"'"'s heart, the method comprising the steps of:

gathering electogram (EGM) data from a heart via an implantable medical device (IMD);

processing the EGM data to isolate an ST segment for the patient;

determining if the ST segment is one of elevated from a baseline and depressed from a baseline, and in the event that the ST segment is deemed elevated then classifying the event as an acutely severe episode of cardiac ischemia and in the event that the ST segment is deemed depressed then classifying the event as a relatively benign ischemic episode;

in the event that the ST segment is deemed depressed, then evaluating accelerometer data to determine is the ischemic episode can be further classified as one of a stable episode and an unstable episode; and

issuing a response to the patient, wherein the response is determined as a function of whether the ischemic episode is one of;

an acutely severe episode and an unstable episode.

11. The method of claim 10 further comprising the step of modulating an anti-ischemia therapy if the classification indicates an unstable ischemic episode.

12. The method of claim 10 further comprising the step of storing data in a memory if a stable ischemic episode is indicated.

13. An implantable medical device for gauging the severity of ischemia in a patient'"'"'s heart, the device comprising:

a data collection module configured to receive electrogram (EGM) data and accelerometer data about the condition of a patient'"'"'s heart;

a data processing module in communication with the data collection module and configured to process the EGM data and the accelerometer data to identify an episode of ischemia in the patient, wherein the data processing module is further configured to evaluate the EGM data and the accelerometer data to determine the relative severity of the episode; and

a response module configured to provide a response to the patient as a function of the severity of the episode, said response including the delivering a modulated anti-ischemia therpy, wherein said therapy is modulated in relation to the relative severity of the episode

wherein the processing module is further configured to identify the episode as a function of a depression in an ST segment portion of the EGM data and

wherein the processing module is further configured to determine if the episode is stable or unstable as a function of the accelerometer data.

14. The device of claim 13 further comprising a response module configured to administer at least one additional anti-schemia therapy if the episode is classified as unstable, said additional anti-schemia therapy comprising one of:

a drug therapy provided from an implantable drug pump and a neurological therapy delivered from an implantable pulse generator.

15. The device of claim 13 wherein the processing module is further operable to compare the episode to the historical data stored in the memory to verify that the episode is consistent with a pattern.

16. An implantable medical device (IMD) for gauging the severity of ischemia in a patient'"'"'s heart, the device comprising:

means for gathering electrogram (EGM) data from an implanted location disposed in electrical communication with a patient'"'"'s heart;

means for processing the EGM data to isolate an ST segment for the patient;

means for determining if the ST segment is one or elevated from and depressed from a baseline level, wherein both an elevated and a depressed ST segment is deemed to indicate the detection of an ischemic episode;

means for evaluating, if the ischemic episode is indicated, an accelerometer-based data set to determine if the ischemic episode is stable or unstable, wherein an accelerometer used to provide the accelerometer-based data set is adapted to mechanically couple to a portion of contractile tissue of the heart; and

means for issuing a response to the patient, wherein the response is determined as a function of whether the ischemic episode is one of a stable episode and an unstable episode.

17. The device of claim 16 wherein the means for evaluating comprises a means for checking historical data regarding at least one prior ischemic episode for the patient to verify that the classified ischemic episode conforms to a historical pattern.