Ultrasonic position indicator

• US 7,068,867 B2
• Filed: 01/02/2003
• Issued: 06/27/2006
• Est. Priority Date: 01/02/2003
• Status: Expired due to Term

• Current Assignee: PHC Holdings Corporation
• Original Assignee: Glucon Medical Ltd. (IntelliDx, Inc.)
• Inventors: Adoram, Avner, Ashkenazi, Shai, Pesach, Benny, Nagar, Ron, Balberg, Michal
• Primary Examiner(s): KANG, JULIANA K
• Application Number:
  US10/335,703
• Publication Number:
  US 20040131299A1
• Time in Patent Office: 1,272 Days
• Field of Search: 385/12, 385/7, 606 1- 3, 606 14- 16
• US Class Current: 385/12
• CPC Class Codes: A61B 17/3403 Needle locating or guiding means guides for suture needles A61B17/0482; guiding or tracking by nuclear magnetic resonance G01R33/285
• CPC Class Codes: A61B 2090/3788 transmitter only
• CPC Class Codes: A61B 5/0095 by applying light and detecting acoustic waves, i.e. photoacoustic measurements
• CPC Class Codes: A61B 5/061 Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body A61B1/00158 takes precedence
• CPC Class Codes: A61B 5/6852 Catheters
• CPC Class Codes: A61B 8/0833 involving detecting or locating foreign bodies or organic structures
• CPC Class Codes: A61B 8/0841 for locating instruments

Abstract

A system for monitoring a position of an instrument in a subject includes a light transmission medium configured to transmit light pulses to a desired region to produce an acoustic signal, at least one ultrasound sensor configured to receive the acoustic signal and to produce a transduced signal from the acoustic signal, and a processing unit connected to the at least one ultrasound sensor and configured to locate a source of the acoustic signal using the transduced signal.

Claims

1. A system for monitoring a position of an instrument in a subject comprising:

a light transmission medium configured to transmit light pulses to a desired region to produce an acoustic signal, wherein the light transmission medium is an optical fiber;

at least one ultrasound sensor configured to receive the acoustic signal and to produce a transduced signal from the acoustic signal;

a processing unit connected to the at least one ultrasound sensor and configured to locate a source of the acoustic signal using the transduced signal; and

a photoacoustic transducer including a photoacoustic material disposed in the desired region to absorb light transmitted by the light transmission medium to produce the acoustic signal, wherein the photoacoustic material is disposed at an end of the optical fiber, and wherein the photoacoustic material is a first photoacoustic material configured to produce a first frequency of sound from absorbed light, the system further comprising a second photoacoustic material configured to produce a second frequency of sound from absorbed light and coupled to the fiber distally from the first material, the first photoacoustic material being disposed and configured to absorb a first portion of light transmitted by the light transmission medium and to pass a second portion of the light transmitted by the light transmission medium.

2. The system of claim 1 wherein the optical fiber is coupled to the instrument.

3. The system of claim 2 wherein the end of the optical fiber, on which the photoacoustic material is disposed, is disposed a known distance from an end of the instrument.

4. A system for monitoring a position of an instrument in a subject comprising:

a light transmission medium configured to transmit light pulses to a desired region to produce an acoustic signal, wherein the light transmission medium comprises a plurality of optical fibers and the system further comprises position indicators coupled to the plurality of fibers;

at least one ultrasound sensor configured to receive the acoustic signal and to produce a transduced signal from the acoustic signal;

a processing unit connected to the at least one ultrasound sensor and configured to locate a source of the acoustic signal using the transduced signal; and

a photoacoustic transducer including a photoacoustic material disposed in the desired region to absorb light transmitted by the light transmission medium to produce the acoustic signal, wherein the photoacoustic material is disposed at an ends of the optical fibers.

5. The system of claim 4 wherein the position indicators comprise photoacoustic transducers including different photoacoustic materials configured to produce different frequencies of ultrasound signals, and wherein the processor is configured to distinguish between the photoacoustic transducers in accordance with the respective frequencies associated with the photoacoustic materials.

6. The system of claim 4 further comprising an optical driver coupled to the processor, wherein the processor is configured to cause the optical driver to provide optical signals to the plurality of optical fibers at different times, and wherein the processor is configured to distinguish between the position indicators in accordance with respective excitation times of the position indicators.

7. The system of claim 4 further comprising the instrument, wherein the position indicators are coupled to the instrument and have ultrasound-emitting portions that are disposed at least one of at known locations relative to the instrument and at known locations relative to each other.

8. The system of claim 4 further comprising a sensor disposed among the plurality of position indicators and coupled to the processor, the processor being further configured to determine distances from the sensor to the position indicators in response to information provided to the processor by the sensor.

9. The system of claim 4 further comprising the instrument, the instrument being further configured to selectively contain the plurality of position indicators and deploy ultrasound-emitting portions of the position indicators outside of the instrument.

10. The system of claim 9 wherein the instrument comprises a retractable sleeve for selectively containing and deploying the position indicators.

11. A system for monitoring a position of an instrument in a subject, the instrument being configured to be inserted into the subject, the system comprising:

an array of ultrasound transducers configured to translate between ultrasound signals and electrical signals;

an optical driver configured to provide optical excitation signals;

a position indicator including an optical fiber, coupled to the optical driver and attached to the instrument, and a photoacoustic material disposed to absorb light transmitted by the optical fiber;

a display configured to provide images in response to control signals; and

a processor connected to the transducers, the optical driver, and the display, and configured to;

actuate the array to emit ultrasound signals into the subject;

receive first electrical signals from the array indicative of reflections of the emitted ultrasound signals;

process the first electrical signals into first control signals indicative of a first image of the subject and to convey the first control signals to the display;

actuate the driver to provide an excitation signal to the optical fiber;

receive a second electrical signal from the array indicative of an ultrasound signal produced by the photoacoustic material;

determine a position of the instrument from the second electrical signal; and

process the second electrical signal into a second control signal indicative of a second image of the instrument and to convey the second control signal to the display.

12. The system of claim 11 wherein the processor is configured to control the display to provide the images from the first and second control signals such that the first and second images at least appear to be provided concurrently.

13. The system of claim 11 wherein the processor is configured to actuate the transmission from the array and to actuate the optical driver at different, alternating times.

14. An instrument for use with an ultrasound imager for monitoring positions associated with the instrument while the instrument is disposed in a subject, the instrument comprising:

a body having a proximal end and a distal end, the body being configured to be inserted into the subject;

a first optical fiber coupled to the body and having a distal end disposed adjacent to the distal end of the body; and

a first photoacoustic material on the first optical fiber configured to transduce optical signals received from the first optical fiber into first ultrasound signals and to emit the first ultrasound signals into the subject, wherein the distal end of the first optical fiber is disposed a known distance from the distal end of the body.

15. The instrument of claim 14 further comprising:

a second optical fiber coupled to the body and having a distal end; and

a second photoacoustic material on the second optical fiber, the second photoacoustic material configured to transduce optical signals received from the second optical fiber into second ultrasound signals and to emit the second ultrasound signals into the subject, the first and second photoacoustic materials being configured such that frequencies of the first and second ultrasound signals are different.

16. The instrument of claim 15 wherein the first and second optical fibers are fixedly coupled to the body along portions of their lengths and distal portions of their lengths releasably contained by the body.

17. The instrument of claim 16 wherein the body includes a sleeve for releasably containing the distal portions of the optical fibers, the sleeve being movable between a first position for containing the distal portions of the fibers and a second position for deploying the distal portions of the fibers.

18. The instrument of claim 15 further comprising an acoustic sensor, configured to transduce acoustic signals, coupled to the body.

19. The instrument of claim 14 wherein the body is configured to be inserted into a human.

20. A system for monitoring the position of an instrument in a subject, the instrument being configured to be inserted into the subject, the system comprising:

a plurality of ultrasound transducers configured to translate between ultrasound signals and electrical signals;

driver means coupled to the ultrasound transducers for providing first excitation signals to the ultrasound transducers and for providing second excitation signals;

position indicator means coupled to the driver and to the instrument for producing ultrasound signals in response to the second excitation signals from the driver means; and

processor means, coupled to the transducers and the driver means, for controlling the driver means to cause the transducers to transmit first ultrasound signals into the subject, for determining an image of the subject from reflected subject signals related to the first ultrasound signals, for controlling the driver means to cause the position indicator means to produce a second ultrasound signals, for determining an indicator image corresponding to the position indicator means from indicator signals related to the second ultrasound signal, and for controlling a display to show an association between the indicator image and the image of the subject.

21. The system of claim 20 wherein the driver means includes an electrical driver coupled to the transducers and an optical driver coupled to the position indicator means.

22. The system of claim 20 wherein the position indicator means includes a photoacoustic material on an optical fiber.

23. The system of claim 22 wherein the position indicator means includes multiple optical fibers each having a photoacoustic material on a respective tip.

24. The system of claim 23 wherein different optical fibers of the position indicator means have different photoacoustic material characteristics that produce different frequencies of ultrasound.

25. The system of claim 20 wherein the position indicator means comprises multiple ultrasound emitters, the system further comprising an acoustic sensor configured to receive and transduce ultrasound from the multiple ultrasound emitters, and to transmit the transduced information to the processing means that is further for determining distances from the acoustic sensor to the multiple ultrasound emitters.