Polynucleotides encoding human GABA receptors

• US 7,074,591 B2
• Filed: 06/27/2001
• Issued: 07/11/2006
• Est. Priority Date: 06/27/2000
• Status: Expired due to Fees

• Current Assignee: Lexicon Genetics, Incorporated
• Original Assignee: Lexicon Genetics, Incorporated
• Inventors: Walke, D. Wade, Friddle, Carl Johan, Mathur, Brian, Turner, C. Alexander Jr.
• Primary Examiner(s): Landsman, Robert S.
• Application Number:
  US09/893,321
• Publication Number:
  US 20020082407A1
• Time in Patent Office: 1,840 Days
• Field of Search: 536/23.5, 435/69.1, 435/70.1, 435/71.1, 435/71.2, 435/252.3, 435/320.1, 435/325, 435/471
• US Class Current: 435/69.1
• CPC Class Codes: C07K 14/70571 for neuromediators, e.g. serotonin receptor, dopamine receptor

Abstract

Novel human polynucleotide and polypeptide sequences are disclosed that can be used in therapeutic, diagnostic, and pharmacogenomic applications.

Claims

1. An isolated nucleic acid molecule comprising a nucleotide sequence encoding an amino acid sequence drawn from the group consisting of SEQ ID NOS:

2 and 4.

5. An expression vector comprising a nucleic acid molecule of claim 1.

6. An isolated cell comprising the expression vector of claim 5.

2. An isolated nucleic acid molecule comprising a nucleotide sequence that:

(a) encodes the amino acid sequence of SEQ ID NO;

2; and

(b) hybridizes under stringent conditions including washing in 0.1×

SSC/0.1% SDS at 68°

C. to the complement of the nucleotide sequence of SEQ ID NO;

1.

3. An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:

1.

4. An isolated nucleic acid molecule comprising the nucleotide sequence of SEQ ID NO:

3.