Estrieno[3,2-b]/[3,4-c]pyrrole derivatives useful as modulators of the estrogen receptors
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention is directed to novel estrieno[3,2-b]/[3,4-c]pyrrole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and diseases mediated by an estrogen receptor.
-
Citations
17 Claims
- 1. A compound of formula (I)
- 5. A compound of the formula (II)
-
11. A method for treating a disorder mediated by an estrogen receptor, wherein the disorder is selected from the group consisting of osteoporosis, hot flashes, vaginal dryness, breast cancer and endometriosis.
-
15. A method for treating a disorder mediated by an estrogen receptor, wherein the disorder is selected from the group consisting of osteoporosis, hot flashes, vaginal dryness, breast cancer and endometriosis.
-
17. A method of contraception comprising co-therapy with a therapeutically effective amount of a compound of formula (II) and a progestogen or a progestogen antagonist, wherein formula (II) is as follows:
Specification