Nucleic acid sequences showing enhanced expression in benign neuroblastoma compared with acritical human neuroblastoma
First Claim
Patent Images
1. An isolated nucleic acid comprising a sequence selected from the group consisting of nucleic acid sequences set forth in SEQ ID NO:
- 3, SEQ ID NO;
5, SEQ ID NO;
9, SEQ ID NO;
19, SEQ ID NO;
22, SEQ ID NO;
32, SEQ ID NO;
40, SEQ ID NO;
55, SEQ ID NO;
56 and SEQ ID NO;
74, in the Sequence Listing or a complementary nucleic acid thereof.
1 Assignment
0 Petitions
Accused Products
Abstract
There are disclosed a nucleic acid which is derived from the gene expressed in human neuroblastoma, and which comprises any sequence selected from the group consisting of the nucleic acid sequences set forth SEQ ID NO:1 to NO:104 in the Sequence Listing, or its complementary nucleic acid; a fragment of the nucleic acid; their use as probes or primers; and the diagnosis of neuroblastoma prognosis using any of the foregoings.
-
Citations
14 Claims
-
1. An isolated nucleic acid comprising a sequence selected from the group consisting of nucleic acid sequences set forth in SEQ ID NO:
- 3, SEQ ID NO;
5, SEQ ID NO;
9, SEQ ID NO;
19, SEQ ID NO;
22, SEQ ID NO;
32, SEQ ID NO;
40, SEQ ID NO;
55, SEQ ID NO;
56 and SEQ ID NO;
74, in the Sequence Listing or a complementary nucleic acid thereof. - View Dependent Claims (2, 3, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
- 3, SEQ ID NO;
-
4. A method of diagnosising the prognosis of human neuroblastoma, said method comprising
extracting a neuroblastoma specimen from a subject; -
detecting at least one nucleic acid in the specimen, the nucleic acid comprising a sequence selected from the group consisting of nucleic acid sequences set forth in SEQ ID NO;
3, SEQ ID NO;
5, SEQ ID NO;
9, SEQ ID NO;
19, SEQ ID NO;
22, SEQ ID NO;
32, SEQ ID NO;
40, SEQ ID NO;
55, SEQ ID NO;
56 and SEQ ID NO;
74, in the Sequence Listing or a complementary nucleic acid thereof; anddiagnosing the prognosis of the human neuroblastoma as favorable if said nucleic acid is detected.
-
Specification