Microelectromechanical system and method for determining temperature and moisture profiles within pharmaceutical packaging

• US 7,089,786 B2
• Filed: 05/12/2003
• Issued: 08/15/2006
• Est. Priority Date: 05/15/2002
• Status: Expired due to Fees

• Current Assignee: Glaxo Group Limited (GSK plc)
• Original Assignee: Glaxo Group Limited (GSK plc)
• Inventors: Walker, Dwight Sherod
• Primary Examiner(s): Raevis, Robert
• Application Number:
  US10/513,841
• Publication Number:
  US 20050223827A1
• Time in Patent Office: 1,191 Days
• Field of Search: None
• US Class Current: 73/73
• CPC Class Codes: B65D 79/02 Arrangements or devices for indicating incorrect storage or transport B65D79/005 takes precedence ; measuring devices G01
• CPC Class Codes: G01K 1/022 for recording
• CPC Class Codes: G01K 1/026 arrangements for monitoring a plurality of temperatures, e.g. by multiplexing
• CPC Class Codes: G01K 5/486 using microstructures, e.g. made of silicon G01K7/015, G01K7/028, G01K7/226, G01K17/006 take precedence
• CPC Class Codes: G01N 35/00009 provided with a sample supporting tape, e.g. with absorbent zones

Abstract

A sensor system for determining at least one environmental condition within pharmaceutical packaging comprising a base sheet with at least one pocket formed therein, a lid sheet having a pocket portion, the pocket portion being disposed proximate the pocket when the lid sheet is bonded to the base sheet; and a microelectromechanical (MEMS) sensor disposed proximate the pocket portion.

Claims

1. A sensor system for determining an environmental condition within pharmaceutical packaging, comprising:

a base sheet having at least one pocket formed therein;

a lid sheet, said lid sheet including a pocket portion, said pocket portion being disposed proximate said pocket when said lid sheet is bonded to said base sheet, said lid sheet and said base sheet forming an internal cavity when said lid sheet is bonded to said base sheet; and

a microelectromechanical sensor disposed proximate said pocket portion, said sensor including a sensing element having a moisture sensitive coating thereon, said sensor providing at least first sensor signal in response to an environmental condition within said internal cavity.

2. A sensor system for determining an environmental condition within pharmaceutical packaging, comprising:

a base sheet having at least one pocket formed therein;

a lid sheet, said lid sheet including a pocket portion, said pocket portion being disposed proximate said pocket when said lid sheet is bonded to said base sheet, said lid sheet and said base sheet forming an internal cavity when said lid sheet is bonded to said base sheet; and

a microelectromechanical sensor disposed proximate said pocket portion, said sensor including a sensing element having a moisture sensitive coating thereon, said moisture sensitive coating changing mass with changes in relative humidity, said sensor providing at least first sensor signal in response to an environmental condition within said internal cavity.

3. A said sensor system for determining an environmental condition within pharmaceutical packaging, comprising:

a base sheet having at least one pocket formed therein;

a lid sheet, said lid sheet including a pocket portion, said pocket portion being disposed proximate said pocket when said lid sheet is bonded to said base sheet, said lid sheet and said base sheet forming an internal cavity when said lid sheet is bonded to said base sheet; and

a microelectromechanical sensor disposed proximate said pocket portion, said sensor including a sensing element having a moisture sensitive coating thereon, said sensing element comprising a cantilever beam, said sensor providing at least first sensor signal in response to an environmental condition within said internal cavity.

4. A sensor system for determining an environmental condition within pharmaceutical packaging comprising:

a base sheet having at least one pocket formed therein;

a lid sheet, said lid sheet including a pocket portion, said pocket portion being disposed proximate said pocket when said lid sheet is bonded to said base sheet, said lid sheet and said base sheet forming an internal cavity when said lid sheet is bonded to said base sheet; and

a microelectromechanical sensor disposed proximate said pocket portion, said sensor including a sensing element having a moisture sensitive coating thereon, said sensing element comprising a cantilever beam, said sensor providing at least first sensor signal in response to an environmental condition within said internal cavity,

wherein adsorption of water vapor by said moisture sensitive coating produces a shear stress at the interface of said sensing element and said moisture sensitive coating, and wherein said moisture sensitive coating is shear restrained by said sensing element.

5. A sensor system for determining an environmental condition within pharmaceutical packaging, comprising:

a base sheet having at least one pocket formed therein;

a lid sheet, said lid sheet including a pocket portion, said pocket portion being disposed proximate said pocket when said lid sheet is bonded to said base sheet, said lid sheet and said base sheet forming an internal cavity when said lid sheet is bonded to said base sheet;

a microelectromechanical sensor disposed proximate said pocket portion, said sensor including a sensing element having a moisture sensitive coating thereon, said moisture sensitive coating changing mass with changes in relative humidity, said sensor providing at least first sensor signal in response to an environmental condition within said internal cavity;

a memory adapted to receive and store said first sensor signal;

a processor for determining at least said environmental condition using said first sensor signal; and

a display in communication with said processor for displaying at least said environmental condition.