High-resolution 3D ultrasonic transmission imaging

• US 7,094,205 B2
• Filed: 04/05/2002
• Issued: 08/22/2006
• Est. Priority Date: 04/06/2001
• Status: Expired due to Term

• Current Assignee: The Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California (University of Southern California)
• Original Assignee: The Alfred E. Mann Institute For Biomedical Engineering At The University Of Southern California (University of Southern California)
• Inventors: Marmarelis, Vasilis Z.
• Primary Examiner(s): Jaworski, Francis J.
• Application Number:
  US10/117,763
• Publication Number:
  US 20030069501A1
• Time in Patent Office: 1,600 Days
• Field of Search: 600/440, 600/441, 600/443, 600/447, 600/448, 736/02, 128915-916
• US Class Current: 600/448
• CPC Class Codes: A61B 8/0825 for diagnosis of the breast, e.g. mammography
• CPC Class Codes: A61B 8/406 using means for diagnosing suspended breasts
• CPC Class Codes: A61B 8/483 involving the acquisition of a 3D volume of data
• CPC Class Codes: A61B 90/17 for soft tissue, e.g. breast-holding devices

Abstract

A system for providing high resolution imaging of objects having sub-millimeter dimensions comprised of at least one transmitter, at least one receiver, a coupling chamber, and a processor for recording attenuation and time of flight profiles of the transmitted signals. The signals are conditioned in a manner to provide high signal-to-noise ration (SNR) and minimal crosstalk and multipath effects at the receiver.

Claims

1. A system for creating an image of an object comprising:

a) at least one transmitter that transmits a signal;

b) at least one receiver positioned to receive the signal;

c) said at least one transmitter including a transducer that has at least two linear dimensions that are no greater than one millimeter;

d) an area between said transmitter and said receiver for receiving the object in a position that causes at least portions of the signal to scatter before the signal is received by said receiver;

e) a processor in communication with said receiver for extracting scattering information from the signal and for creating an image of the object based on the scattering information; and

f) wherein said at least one transmitter and said at least one receiver are operable in transmission mode.

2. The system of claim 1 further including a housing apparatus that fixes said transmitter and said receiver relative to one another and that allows said transmitter and said receiver to move relative to the object.

3. The system of claim 2 wherein said housing apparatus allows said transmitter and said receiver to move relative to the object in at least two different directions.

4. The system of claim 1 further including a housing apparatus that fixes said transmitter and said receiver relative to one another and that allows said transmitter and said receiver to move relative to the object.

5. The system of claim 1 wherein the scattering information includes an attenuation profile and a time of flight profile of the signal.

6. The system of claim 1 wherein said at least one transmitter and said at least one receiver are affixed on a surface of an enclosure.

7. The system of claim 6 wherein the enclosure is configured to hold a fluid.

8. The system of claim 1 wherein the signal transmitted by said at least one transmitter is an ultrasonic signal.

9. The system of claim 1 wherein said at least one receiver includes a transducer having no linear dimension greater than one millimeter.

10. A system for creating an image of an object that has at least one linear dimension of less than one millimeter comprising:

a) at least one transmitter that transmits a signal;

b) at least one receiver positioned to receive the signal;

c) an area between said transmitter and said receiver for receiving the object in a position that causes at least portions of the signal to be scattered before the signal is received by said receiver;

d) a processor in communication with said receiver for creating a discernable image of the dimension of the object that is less than one millimeter;

e) wherein the at least one transmitter has at least two linear dimensions that are no greater than one millimeter; and

f) wherein the at least one transmitter and the at least one receiver are operable in transmission mode.

11. The system of claim 10 further including a housing apparatus that fixes said transmitter and said receiver relative to one another and that allows said transmitter and said receiver to move relative to the object.

12. The system of claim 11 wherein said housing apparatus allows said transmitter and said receiver to move relative to the object in at least two different directions.

13. The system of claim 10 wherein said at least one transmitter and said at least one receiver are affixed on a surface of an enclosure.

14. The system of claim 13 wherein the enclosure is configured to hold a fluid.

15. The system of claim 10 wherein the signal transmitted by the at least one transmitter is an ultrasonic signal.

16. The system of claim 10 wherein the processor includes a system for extracting an attenuation profile and a time of flight profile from the signal and for creating the image of the object based on these profiles.

17. The system of claim 10 wherein said at least one receiver includes a transducer having no linear dimension greater than one millimeter.

18. A method for creating an image of object positioned in an area between a transmitter and a receiver comprising:

a) transmitting a signal from at least one transmitter;

b) receiving a signal through at least one receiver;

c) the at least one transmitter including a transducer that has at least two linear dimensions that are no greater than one millimeter;

d) extracting scattering information from the received signal;

e) creating an image of the object based on the scattering information; and

f) wherein said at least one transmitter and said at least one receiver are operable in transmission mode.

19. The method of claim 18 further comprising moving said transmitter and said receiver relative to the object.

20. The method of claim 19 wherein the moving is in at least two different directions.

21. The system of claim 18 wherein the scattering information includes an attenuation profile and a time of flight profile of the signal.

22. The method of claim 18 wherein said at least one transmitter and said at least one receiver are affixed on a surface of an enclosure.

23. The method of claim 22 wherein the enclosure is configured to hold a fluid.

24. The method of claim 18 wherein the signal transmitted by said at least one transmitter is an ultrasonic signal.

25. The method of claim 18 wherein said at least one receiver includes a transducer having no linear dimension greater than one millimeter.

26. A system for creating an image of an object comprising:

a) at least one transmitter that transmits a signal;

b) at least one receiver positioned to receive the signal;

c) an area between said transmitter and said receiver for receiving the object in a position that causes at least portions of the signal to be scattered before the signal is received by said receiver;

d) a processor in communication with said receiver for creating an image of the object;

e) wherein said at least one transmitter includes a transducer having at least two linear dimensions that are no greater than one millimeter; and

f) wherein said at least one transmitter and said at least one receiver are operable in transmission mode.

27. The method of claim 26 wherein said at least one receiver includes a transducer having no linear dimension greater than one millimeter.

28. A system for creating an image of an object comprising:

a) at least one transmitter that transmits a signal;

b) at least one receiver positioned to receive the signal;

c) an area between said transmitter and said receiver for receiving the object in a position that causes at least portions of the signal to be altered before the signal is received by said receiver;

d) a processor in communication with said receiver for creating an image of the object;

e) wherein said at least one transmitter includes a transducer having at least two linear dimensions that are no greater than one millimeter; and

f) wherein said at least one transmitter and said at least one receiver are operable in transmission mode.

29. The system of claim 28 wherein the at least portions of the signal are altered through scattering by the object.

30. The system of claim 28 wherein said at least one receiver includes a transducer having no linear dimension greater than one millimeter.