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Method of obtaining immune cells from an animal

  • US 7,094,419 B2
  • Filed: 06/24/2003
  • Issued: 08/22/2006
  • Est. Priority Date: 05/11/2001
  • Status: Expired due to Fees
First Claim
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1. A method of obtaining immune cells from an animal comprising harvesting immune cells from an immune modulation device comprised of an impermeable biocompatible shell having an outer surface with plurality of pores of suitable size to allow the ingress and egress of immune cells and said impermeable biocompatible shell having an interior lumen, a biocompatible fibrous scaffolding being disposed within said interior lumen, said fibrous scaffolding comprising textured yarn containing crimped fibers having crimp points, wherein the orientation of filaments in said crimped fiber changes angle at said crimp points;

  • said interior lumen having therein a quantity of antigen or chemotatic agent sufficient to provoke an immune response that was implanted within an animal time sufficient to allow immune cells to migrate into the immune modulation device.

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