Active fluid delivery catheter

• US 7,103,418 B2
• Filed: 10/02/2002
• Issued: 09/05/2006
• Est. Priority Date: 10/02/2002
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Sommer, John L., Laske, Timothy G., Sigg, Daniel C.
• Primary Examiner(s): Bockelman, Mark
• Application Number:
  US10/262,046
• Publication Number:
  US 20040068299A1
• Time in Patent Office: 1,434 Days
• Field of Search: 607/116, 607/119, 607/120, 607/122, 607126-128, 604/506, 604/175, 604/272
• US Class Current: 607/120
• CPC Class Codes: A61M 2025/0089 Single injection needle protruding axially, i.e. along the longitudinal axis of the catheter, from the distal tip
• CPC Class Codes: A61M 2025/0095 being one or more needles protruding from the distal tip and which are not used for injection nor for electro-stimulation, e.g. for fixation purposes
• CPC Class Codes: A61M 25/0026 Multi-lumen catheters with stationary elements catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175
• CPC Class Codes: A61M 25/0082 Catheter tip comprising a tool
• CPC Class Codes: A61M 25/0084 being one or more injection needles
• CPC Class Codes: A61N 1/05 for implantation or insertion into the body, e.g. heart electrode A61N1/06 takes precedence
• CPC Class Codes: A61N 1/0575 with drug delivery
• CPC Class Codes: A61N 1/0587 Epicardial electrode systems; Endocardial electrodes piercing the pericardium

Abstract

A medical system incorporating fluid delivery and lead delivery lumens dispense fluid into a volume of tissue. The fluid comprises or contains a pharmacologic, genetic, or biologic agent. The fluid may be dispensed initially during implantation or later using a minimally invasive medical procedure.

Claims

1. An implantable fluid delivery system comprising:

an elongate guide catheter having at least one elongated fluid delivery lumen and at least one medical electrode lead lumen disposed therein;

a hollow, perforated fixation member in fluid communication with said at least one fluid delivery lumen, said fixation member having one of a helical coil or a fish hook configuration;

at least one medical electrode lead member having a distal end said lead removably disposed in said at least one medical electrode lead lumen whereby the guide catheter may be removed from the body leaving the medical electrode therein, said medical electrode lead having a fixation member adjacent said distal end and being extendable from said medical electrode lead lumen, said fixation member having one of a helical coil or a fish hook configuration.

2. A system according to claim 1, wherein said medical electrical lead further comprises an electrical conductor disposed within a lead body portion and said electrical conductor is electrically coupled to said electrode structure adapted to contact tissue and said electrical conductor electrically couples to a one of the following:

an implantable pulse generator, a positive pressure drug pump, a negative pressure drug pump, a micro-osmotic pump, a positive displacement pump, a solenoid-activated pump, a neurostimulator, a pacemaker, an ICD.

3. A system according to claim 2, wherein said tissue is at least a portion of one of the following types of tissue:

a cardiac tissue, a nerve tissue, a muscle tissue, an organ tissue, a central nervous system tissue, a brain tissue.

4. A system according to claim 1, wherein a proximal end of said guide-catheter is sealed and adapted to be disposed proximate a portion of epidermis of a patient.

5. A system according to claim 1, wherein said guide-catheter further comprises a steerable catheter and said steerable catheter comprises a manually adjustable handle means mechanically coupled to a proximal end of the guide-catheter for providing torque to the proximal portion of said guide-catheter.

6. A system according to claim 5, wherein said handle means mechanically couples to a proximal portion of at least one pull wire and wherein said at least one pull wire is mechanically coupled to a distal portion of said guide-catheter.

7. A system according to claim 6, further comprising a fluid reservoir fluidly coupled to a delivery port of said handle means and wherein said delivery port is in fluid communication with said at least one fluid delivery lumen.

8. A system according to claim 7, wherein a fluid is pre-filled into said fluid reservoir, said fluid comprising a pharmacological agent, a genetic agent, or a biological agent.

9. A method for guiding an irrigated active fixation means to a portion of tissue, piercing said portion of tissue and dispensing a fluid therein, comprising:

advancing a guide-catheter to a portion of tissue, wherein said guide catheter has at least one fluid delivery lumen disposed therein;

piercing said portion of tissue with an irrigated tip portion of said guide-catheter, wherein said guide-catheter is fluidly coupled to the at least one fluid delivery lumen;

dispensing a fluid into said pierced portion of tissue through said fluid delivery lumen and said irrigated tip portion, said fluid is a pharmacological agent, a genetic agent, or a biological agent;

retracting said irrigated tip portion into a distal portion of said guide catheter;

delivering a medical electrical lead through at least one lead-delivery lumen of said guide-catheter to a location adjacent said portion of tissue; and

removing said guide catheter so that said medical electrical lead remains in the location adjacent said portion of tissue.

10. A method according to claim 9, further comprising:

reversing said irrigated tip portion from an original insertion depth and again dispensing the fluid.

11. A method according to claim 9, wherein said dispensing is a single shot bolus delivery.

12. A method comprising:

advancing a guide-catheter to a portion of tissue, wherein said guide catheter has at least one fluid delivery lumen disposed therein;

piercing said portion of tissue with an irrigated tip portion of said guide-catheter, wherein said guide-catheter is fluidly coupled to the at least one fluid delivery lumen;

dispensing a fluid into said pierced portion of tissue through said fluid delivery lumen and said irrigated tip portion; and

delivering a medical electrical lead with an active fixation electrode tip through at least one lead-delivery lumen of said guide-catheter to a location adjacent said portion of tissue, and implanting said active fixation electrode tip in said tissue,

removing said guide catheter from the body leaving the electrical lead implanted in said tissue.