Method and apparatus for optimizing ventricular synchrony during DDD resynchronization therapy using adjustable atrio-ventricular delays
First Claim
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1. A system, comprising:
- a signal input to receive at least one cardiac signal indicative of cardiac events including at least one atrial event and one ventricular event;
an event detector, coupled to the signal input, to detect the at least one atrial event and one ventricular event;
a measurement module, coupled to the event detector, to measure an atrio-ventricular time interval (AV) between an atrial event and a ventricular event of the at least one atrial event and one ventricular event; and
an atrio-ventricular delay (AVD) calculator coupled to the measurement module, the AVD calculator adapted to calculate an AVD using the AV and a predetermined equation relating the AV to an optimal AVD to provide a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, by delivering ventricular pacing pulses with the optimal AVD.
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Abstract
A pacing system for providing optimal hemodynamic cardiac function for parameters such as ventricular synchorny or contractility (peak left ventricle pressure change during systole or LV+dp/dt), or stroke volume (aortic pulse pressure) using system for calculating atrio-ventricular delays for optimal timing of a ventricular pacing pulse. The system providing an option for near optimal pacing of multiple hemodynamic parameters. The system deriving the proper timing using electrical or mechanical events having a predictable relationship with an optimal ventricular pacing timing signal.
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Citations
16 Claims
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1. A system, comprising:
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a signal input to receive at least one cardiac signal indicative of cardiac events including at least one atrial event and one ventricular event; an event detector, coupled to the signal input, to detect the at least one atrial event and one ventricular event; a measurement module, coupled to the event detector, to measure an atrio-ventricular time interval (AV) between an atrial event and a ventricular event of the at least one atrial event and one ventricular event; and an atrio-ventricular delay (AVD) calculator coupled to the measurement module, the AVD calculator adapted to calculate an AVD using the AV and a predetermined equation relating the AV to an optimal AVD to provide a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, by delivering ventricular pacing pulses with the optimal AVD. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A computer-readable medium, comprising:
computer-executable instructions to cause a computer or computer-based system to perform functions comprising; receiving an atrio-ventricular time interval (AV) between an atrial event and a ventricular event; and calculating an atrio-ventricular delay (AVD) using the AV and a predetermined equation relating the AV to an optimal AVD to provide a maximum positive rate of left ventricular pressure change during systole, LV+dp/dt, and delivering ventricular pacing pulses with the optimal AVD. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16)
Specification