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First Claim
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1. An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus comprising:
- a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used;
b) a frame for supporting the substrate;
c) a detector configured to detect light;
d) an optical relay configured to transmit light from at least one of the light sources to one of the plurality of sample sites and from the sample site to the detector; and
e) a support structure for supporting the moveable support, the frame, the detector and the optical relay;
wherein the moveable support is moveable independently of the optical relay.
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Abstract
An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus having an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; a frame for supporting the substrate; a detector configured to detect light; an optical relay configured to transmit light from at least one of the plurality of light sources to a sample site and from the sample site to the detector; and a support structure for supporting the frame, the detector and the optical relay.
30 Citations
20 Claims
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1. An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one of the light sources to one of the plurality of sample sites and from the sample site to the detector; and e) a support structure for supporting the moveable support, the frame, the detector and the optical relay; wherein the moveable support is moveable independently of the optical relay. - View Dependent Claims (2, 7, 8, 9, 18)
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3. An apparatus for analyzing a plurality of samples in samples sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one of the light sources to one of the plurality of sample sites and from the sample site to the detector; and e) a support structure for supporting the frame, the detector and the optical relay; wherein the frame is configured to move the substrate in a first direction so that the sample sites pass sequentially through an examination region.
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4. An apparatus for analyzing a plurality of samples in samples sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one of the light sources to one of the plurality of sample sites and from the sample site to the detector; and e) a support structure for supporting the frame, the detector and the optical relay; wherein the moveable support is a rotatable wheel.
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5. An apparatus for analyzing a plurality of samples in samples sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one of the light sources to one of the plurality of sample sites and from the sample site to the detector; and e) a support structure for supporting the frame, the detector and the optical relay; wherein the moveable support further comprises an aperture for the passage of light from an exterior light source not positioned on the moveable support. - View Dependent Claims (6)
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10. An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one light source to one of the sample sites on the substrate and from the sample site to the detector; and e) a support structure for supporting the stage, the detector and the optical relay; wherein the optical relay further comprises a beam splitter for splitting light from at least one of the array of light sources into two beams, a first beam being directed to an upper surface of the sample site, and a second beam directed to a lower surface of the sample site. - View Dependent Claims (11, 12, 13, 14, 15, 16)
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17. An apparatus for analyzing a plurality of samples in sample sites on a substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a moveable support so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one light source to one of the sample sites on the substrate and from the sample site to the detector; and e) a support structure for supporting the stage, the detector and the optical relay; wherein the optical relay further comprises; a beam splitter for splitting light from at least one of the array of light sources into two beams, a first beam being directed to an upper surface of the sample site, and a second beam directed to a lower surface of the sample site; and a means for blocking at least one of the first beam and the second beam. - View Dependent Claims (20)
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19. An apparatus for analyzing a plurality of samples in sample sites on substrate, the apparatus comprising:
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a) an array of spaced apart light sources coupled to a rotatable wheel so that one or more of the light sources can be selectively used; b) a frame for supporting the substrate; c) a detector configured to detect light; d) an optical relay configured to transmit light from at least one light source to one of the sample sites on the substrate and from the sample site to the detector, the optical relay further comprising; a beam splitter for splitting light from at least one of the array of light sources two beams, a first beam being directed to an upper surface of the sample site, and a second beam directed to a lower surface of the sample site; and a first shutter selectively moveable to block the first beam; and a second shutter selectively moveable to block the second beam; and e) a support structure for supporting the stage, the detector and the optical relay; and wherein at least one of the light sources is an LED.
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Specification