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Method for enabling delivery of an active agent

  • US 7,115,277 B2
  • Filed: 12/02/2002
  • Issued: 10/03/2006
  • Est. Priority Date: 03/04/1999
  • Status: Expired due to Fees
First Claim
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1. An improvement to a method for enabling delivery of Tazarotene, the method comprising the steps of:

  • manufacturing a fill formulation by dissolving Caprylic/Capric Triglyceride (CCT) butylated hydroxytoluene and hereafter dissolving the Tazarotene thereinto;

    adding Polysorbate 80 and Sorbiton Monooleate to the CCT, butylated hydroxyanide, and Tazarotene to form a bulk solution;

    mixing the bulk solution until homogeneous; and

    encapsulating the homogeneous bulk solution into a capsule,said improvement comprising;

    distributing educational materials to medical office personnel including prescribers who are qualified to prescribe the capsules for patients, said educational materials including information as to what the patients need to know and what the patients must do in order to both avoid adverse side effects while taking the capsules and to receive a prescription for the capsules; and

    providing guidelines for counseling the patients with regard to what the patients need to know and what the patients must do in order to both avoid the adverse side effect while taking the capsules and to receive prescriptions for the capsules.

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