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Modified ADAMTS4 molecules and method of use thereof

  • US 7,118,902 B2
  • Filed: 07/29/2003
  • Issued: 10/10/2006
  • Est. Priority Date: 07/29/2002
  • Status: Expired due to Fees
First Claim
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1. An isolated, modified, human ADAMTS4 protein comprising(a) an ADAMTS4 catalytic domain wherein the glutamate at the position corresponding to position 362 of SEQ ID NO:

  • 1 is substituted with a glutamine, and(b) a disintegrin domain.

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