Satiation devices and methods

• US 7,121,283 B2
• Filed: 03/04/2004
• Issued: 10/17/2006
• Est. Priority Date: 08/27/2001
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Synecor LLC
• Inventors: Glenn, Richard A., Stack, Richard S., Moody, Trevor J., Eubanks, William S. Jr., Silverstein, Fred E., Every, Nathan
• Primary Examiner(s): Isabella, David J.
• Application Number:
  US10/794,346
• Publication Number:
  US 20040172142A1
• Time in Patent Office: 957 Days
• Field of Search: 128/898, 623/1.1, 623/11.11, 623/23.64, 623/23.65, 600/97, 606213-219, 606/139, 606/192, 604/909
• US Class Current: 128/898
• CPC Class Codes: A61F 2/04 Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts A61F2/18, A61F2/20 take precedence; devices, other than stent-grafts, providing patency to, or preventing collapsing of, tubular structures of the body other than stent-grafts, e.g. stents A61F2/82; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/24 Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
• CPC Class Codes: A61F 2002/044 Oesophagi or esophagi or gullets
• CPC Class Codes: A61F 2002/045 Stomach, intestines
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/8483 Barbs
• CPC Class Codes: A61F 2250/0039 differing in diameter
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 5/0069 in the wall of the stomach
• CPC Class Codes: A61F 5/0076 preventing normal digestion, e.g. Bariatric or gastric sleeves
• CPC Class Codes: A61F 5/0079 Pyloric or esophageal obstructions

Abstract

A device for inducing weight loss in a patient includes a tubular prosthesis self-expandable from a collapsed position in which the prosthesis has a first diameter to an expanded position in which the prosthesis has a second, larger, diameter. In a method for inducing weight loss, the prosthesis is placed in the collapsed position and inserted into a stomach of a patient. The prosthesis is allowed to self-expand from the collapsed position to the expanded position and into contact with the walls of the stomach, where it induces feelings of satiety and/or inhibits modulation of satiety-controlling factors such as Ghrelin.

Claims

1. A method of inducing weight loss in a patient, comprising the steps of:

positioning a flow-restrictive device in the stomach;

coupling the flow-restrictive device to tissue of the gastro-esophageal junction region of the stomach; and

causing food ingested by the patient to flow into contact with the flow-restrictive device, the flow-restrictive device causing the ingested food to flow at a rate that is slower than a rate at which the food would flow in the absence of the flow restrictive device.

2. The method of claim 1, wherein the positioning step includes positioning the flow-restrictive device in the region of the distal end of the esophagus.

3. The method of claim 1, wherein the flow-restrictive device causes the ingested food to flow from the esophagus into the stomach at a rate that is slower than a rate at which the food would flow in the absence of the flow restrictive device.

4. The method of claim 1, wherein the flow-restrictive devices causes an accumulation of food upstream of the flow-restrictive device.

5. The method of claim 1, wherein the flow restrictive device is a pouch.

6. The method of claim 1, wherein the flow-restrictive device defines a bi-directional flow path in the gastro-esophageal junction region.

7. The method of claim 1, wherein the coupling step includes coupling the flow-restrictive device to a tissue plication.

8. The method of claim 1, wherein the flow-restrictive device is self-expandable, and wherein the method includes allowing the flow restrictive device to self-expand within the gastro-esophageal junction region.