×

Process for aligning macromolecules by passage of a meniscus and applications

  • US 7,122,647 B2
  • Filed: 02/13/2003
  • Issued: 10/17/2006
  • Est. Priority Date: 02/11/1994
  • Status: Expired due to Fees
First Claim
Patent Images

1. A product obtained by a process for detecting a macromolecule in a sample, wherein the process comprises:

  • (a) providing a support having a surface, wherein the surface comprises a molecule with biological activity attached thereto and wherein the molecule with biological activity comprises biotin, a protein, a nucleic acid, a lipid, or a polysaccharide;

    (b) contacting the sample with the surface to couple the macromolecule in the sample to the molecule with biological activity;

    (c) passing a meniscus over the coupled complex from step (b) to align the coupled complex on the surface; and

    (d) detecting, either directly or indirectly, the macromolecule in the coupled complex;

    wherein the product comprises the surface on which the coupled complex is adherent and stationary.

View all claims
  • 0 Assignments
Timeline View
Assignment View
    ×
    ×