×

Electrodes linked via conductive oligomers to nucleic acids

  • US 7,125,668 B2
  • Filed: 09/05/2002
  • Issued: 10/24/2006
  • Est. Priority Date: 11/05/1996
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method of detecting a mismatch in a target sequence, comprisinga) hybridizing a probe nucleic acid to said target sequence to form a hybridization complex comprising said mismatch, wherein said probe nucleic acid is covalently attached to a first electron transfer moiety comprising an electrode, wherein said hybridization complex comprises a second electron transfer moiety, and wherein said electrode further comprises a monolayer;

  • andb) detecting electron transfer between said electrode and said second electron transfer moiety as an indicator of the presence or absence of said mismatch.

View all claims
  • 4 Assignments
Timeline View
Assignment View
    ×
    ×