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Animal tissue with carbohydrate antigens compatible for human transplantation

  • US 7,126,039 B2
  • Filed: 03/21/2002
  • Issued: 10/24/2006
  • Est. Priority Date: 03/21/2001
  • Status: Active Grant
First Claim
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1. A transgenic pig whose genome comprises a homozygous inactivation of the α

  • 1,3GT gene, and wherein said genome further comprises a DNA sequence encoding α

    1,2FT, operably linked to a promoter and expressed wherein cells, tissue, or organs of said pig exhibit reduced hyperacute rejection.

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