Positioning systems and methods for guided ultrasound therapy systems

• US 7,128,711 B2
• Filed: 03/25/2002
• Issued: 10/31/2006
• Est. Priority Date: 03/25/2002
• Status: Expired due to Term

• Current Assignee: InSightec Ltd.
• Original Assignee: InSightec Ltd.
• Inventors: Medan, Yoav, Ezion, Avner
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): Jung, William C
• Application Number:
  US10/106,562
• Publication Number:
  US 20030181806A1
• Time in Patent Office: 1,681 Days
• Field of Search: 601/2, 601/3, 601/4, 600/437, 600/439, 600/410, 600/411, 600/407, 600/421, 324/307, 324/309, 324/316
• US Class Current: 600/439
• CPC Class Codes: A61B 17/2255 Means for positioning patient, shock wave apparatus or locating means, e.g. mechanical aspects, patient beds, support arms, aiming means positioning of patients for radiation diagnosis A61B6/04; positioning of locating means inside shock wave apparatus A61B17/2256
• CPC Class Codes: A61B 17/2256 with means for locating or checking the concrement, e.g. X-ray apparatus, imaging means A61B17/2255 takes precedence
• CPC Class Codes: A61B 2034/2063 Acoustic tracking systems, e.g. using ultrasound
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 8/4209 by using holders, e.g. positioning frames

Abstract

Systems and methods are provided for positioning a therapy device, such as an ultrasound transducer, using a tilt sensor carried by the transducer and a positioner coupled to the transducer. The positioner provides roll and pitch control as well as translating the transducer in lateral and longitudinal directions. A processor receives signals from the tilt sensor corresponding to the actual rotational orientation of the transducer and controls the positioner to adjust the orientation of the therapy device until a desired position is achieved.

Claims

1. A system for directing therapeutic acoustic energy to a target tissue region in a body of a patient during a therapeutic or diagnostic procedure, comprising:

an acoustic transducer positionable outside of the patient'"'"'s body for directing therapeutic acoustic energy emitted by the transducer to the target tissue region, the transducer laterally translatable and capable of at least one of pitch motion and roll motion;

a positioner connected to the transducer for adjusting a position of the transducer, the position being both a location and an orientation of the transducer;

a sensor fixed on the transducer such that a rotational orientation of the sensor is correlated to a rotational orientation of the transducer, the sensor adapted for measuring the position of the transducer, wherein the sensor is a tilt sensor, the tilt sensor generating signals related to at least one of a roll angle and a pitch angle of the transducer relative to one or more axes; and

a processor coupled to the sensor for receiving signals from the sensor related to the measured position of the transducer, the processor coupled to the positioner for directing the positioner to adjust the position of the transducer during the procedure based at least in part on the signals received from the sensor.

2. The system of claim 1, wherein the tilt sensor generates signals related to a roll angle of the transducer about a first horizontal axis, and a pitch angle of the transducer about a second horizontal axis that is orthogonal to the first horizontal axis.

3. The system of claim 1, wherein the positioner comprises a support for rotating the transducer about the one or more axes.

4. The system of claim 1, wherein the sensor is a location sensor, and where the system further comprises an apparatus for detecting the location sensor within a region of space.

5. The system of claim 4, wherein the apparatus for detecting the location sensor comprises an MRI system configured for detecting a position of the location sensor within an MR imaging field of the MRI system.

6. The system of claim 1, wherein the sensor comprises an accelerometer.

7. The system of claim 1, wherein the sensor is contained within non-magnetic packaging.

8. The system of claim 1, wherein the positioner comprises one or more motors coupled to the transducer for at least one of translating the transducer within a plane and rotating the transducer about an axis.

9. The system of claim 8, wherein each of the one or more motors comprises:

a drive shaft coupled to the transducer; and

a piezoelectric element coupled to the drive shaft for rotating the drive shaft.

10. The system of claim 1, further comprising:

a MRI system comprising an imaging volume, wherein the transducer is disposed within the imaging volume, and wherein the positioner is coupled to the transducer for adjusting a position of the transducer within the imaging volume.

11. The system of claim 1, wherein the sensor repeats iterations of measuring the position of the acoustic transducer and the positioner repeats adjusting the position of the acoustic transducer during the procedure until the acoustic transducer is placed in a desired position.

12. The system of claim 1, wherein the acoustic transducer is laterally translatable and capable of both pitch motion and roll motion.

13. The system of claim 1, wherein the sensor is mounted internally within the acoustic transducer.

14. A therapeutic system, comprising:

a therapy device positionable outside of a body of a patient for directing therapeutic energy emitted by the therapy device to a target tissue region within the patient'"'"'s body, the therapy device laterally translatable and capable of at least one of pitch motion and roll motion;

a positioner connected to the therapy device for adjusting a position of the therapy device, the position being both a location and an orientation of the therapy device;

a sensor fixed on the therapy device such that a rotational orientation of the sensor is correlated to a rotational orientation of the therapy device, the sensor adapted for measuring the position of the therapy device, wherein the sensor is a tilt sensor, the tilt sensor generating signals related to at least one of a roll angle and a pitch angle of the transducer relative to one or more axes; and

a processor coupled to the sensor and the positioner, the processor configured to control operation of the positioner during a therapeutic procedure based at least in part on a measured position of the therapy device by the sensor.

15. The system of claim 14, wherein the therapy device comprises an ultrasonic transducer, and the sensor comprises an accelerometer mounted to the transducer for measuring a tilt angle of the transducer.

16. The system of claim 14, wherein the sensor repeats iterations of measuring the position of the therapy device and the positioner repeats adjusting the position of the therapy device during the therapeutic procedure until the therapy device is placed in a desired position.

17. The system of claim 14, wherein the therapy device is laterally translatable and capable of both pitch motion and roll motion.

18. The system of claim 14, wherein the sensor is mounted internally within the therapy device.

19. A method for positioning a therapeutic or diagnostic device during a therapeutic or diagnostic procedure, comprising:

adjusting a position of the device towards a desired position outside a body of a patient within a reference frame, the device being laterally translatable and capable of at least one of pitch motion and roll motion, and the position being both a location and an orientation of the device;

measuring an actual position of the device within the reference frame using a sensor fixed on the device so that a rotational orientation of the sensor is correlated to a rotational orientation of the device, wherein the sensor is a tilt sensor, the tilt sensor generating signals related to at least one of a roll angle and a pitch angle of the transducer relative to one or more axes;

comparing the actual position with the desired position; and

during the therapeutic or diagnostic procedure, actuating a positioner to further adjust the position of the device based on a result of comparing the actual position with the desired position.

20. The method of claim 19, wherein the actuating is performed based upon a difference between the actual position and the desired position.

21. The method of claim 19, wherein the device comprises an ultrasonic transducer.

22. The method of claim 19, wherein the sensor carried by the device is a tilt sensor, and wherein the measuring step comprises measuring an actual rotational orientation of the device with the tilt sensor.

23. The method of claim 22, wherein the positioner is actuated to adjust a rotational orientation of the device.

24. The method of claim 19, wherein the device is disposed within an imaging field of an MRI system, and wherein the measuring step comprises detecting a position of the sensor carried by the device to determine an actual position of the device.

25. The system of claim 19, wherein iterations of measuring, comparing and adjusting are repeated during the therapeutic or diagnostic procedure until the device is placed in a desired position.

26. The method of claim 19, the step of measuring comprising measuring the actual position of the device using a sensor that is mounted internally within the device.