Non-contact waveform monitor

• US 7,128,714 B1
• Filed: 12/24/2003
• Issued: 10/31/2006
• Est. Priority Date: 12/24/2003
• Status: Active Grant

• Current Assignee: the united states of america as represented by the secretary of the navy
• Original Assignee: the united states of america as represented by the secretary of the navy
• Inventors: Lomba, John F., Antonelli, Lynn T., Ohley, William J.
• Primary Examiner(s): Marmor, II, Charles A
• Assistant Examiner(s): Toth, Karen E
• Application Number:
  US10/748,923
• Time in Patent Office: 1,042 Days
• Field of Search: 600/485, 600/513, 600/504, 600/481
• US Class Current: 600/485
• CPC Class Codes: A61B 5/0059 using light, e.g. diagnosis by transillumination, diascopy, fluorescence A61B5/0093, A61B5/1455, A61B5/02416 and A61B5/0261 take precedence
• CPC Class Codes: A61B 5/021 Measuring pressure in heart or blood vessels A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/02108 from analysis of pulse wave characteristics
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/113 occurring during breathing

Abstract

A non-contact method and apparatus for continuously monitoring a physiological event in a human or animal, such as blood pressure, which involves utilizing a laser-based interferometer system to produce a waveform that is representative of continuous blood pressure in a subject. The invention may preferably utilize a laser Doppler vibrometer which is oriented to produce a laser beam directed toward the subject substantially perpendicular to a skin surface of the subject wherein the skin surface is moveable in response to blood pressure. The vibrometer is sensitive to motion of the skin surface in a direction parallel to the laser beam and produces a signal representative of this motion. By plotting the velocity of the skin surface movement in the direction parallel to the laser beam with respect to time, a waveform is produced that has been found to be representative of the blood pressure waveform and highly defined to thereby permit accurate timing analysis thereof relating to cardiac cycles.

Claims

1. An apparatus for continuously measuring a physiological event of a subject, comprising:

a laser source capable of directing a laser beam toward the subject that will reflect said laser beam at a skin region of the subject wherein said skin region is moveable in response to said physiological event; and

a detector comprising a laser interferometer that employs interferometer techniques to detect said reflected laser beam and determine at least a velocity of said skin surface at a given moment in time.

2. The apparatus of claim 1, further comprising a processor joined in communication with said detector for analyzing said velocity with respect to time thereby analyzing said physiological event.

3. The apparatus of claim 1, further comprising a single housing to contain said laser source and said detector.

4. The apparatus of claim 2, wherein said processor produces a waveform representation of said physiological event by plotting said velocity of said skin surface with respect to time and further comprising:

a means for displaying said velocity with respect to time thereby displaying said physiological event.

5. The apparatus of claim 4, wherein said physiological event is a blood pressure of the subject and wherein said waveform representation is representative of a blood pressure waveform and contains dicrotic notch information.

6. The apparatus of claim 4, wherein said physiological event is a rate of respiration of the subject.

7. The apparatus of claim 5, wherein said processor analyzes said blood pressure to determine systolic time interval parameters.

8. The apparatus of claim 5, wherein said processor analyzes said blood pressure to determine heart rate.

9. The apparatus of claim 8, wherein said processor compares systolic time interval parameters estimated utilizing said heart rate with systolic time interval parameters determined from said blood pressure.

10. A method for continuously measuring a physiological event of a subject, comprising:

directing a laser beam toward a skin surface of said subject that will reflect said laser beam wherein said skin surface is moveable in response to said physiological event;

detecting said reflected laser beam by utilizing a laser interferometer and interferometer techniques for detecting said reflected laser beam and through said detection determining said one or more variables related to movement of said skin surface;

determining at least one variable related to movement of said skin surface; and

analyzing said at least one variable related to movement of said skin surface thereby producing a metric concerning said physiological event.

11. The method of claim 10, wherein said physiological event is blood pressure.

12. The method of claim 10, wherein said physiological event is respiration.

13. The method of claim 10, wherein the metric concerning said physiological event is the velocity of said skin surface.

14. The method of claim 10, further comprising displaying said metric concerning said physiological event.

15. The method of claim 13, wherein said physiological event is a blood pressure and further comprising the step of producing a blood pressure waveform representation containing dicrotic notch information by plotting skin surface velocity with respect to time.

16. The method of claim 15, further comprising the step of analyzing said blood pressure waveform representation to determine systolic time interval parameters.

17. The method of claim 15, further comprising the step of analyzing said blood pressure waveform parameters to determine heart rate.

18. The method of claim 17, further comprising the step of comparing systolic time interval parameters estimated utilizing said heart rate with systolic time interval parameters determined from said blood pressure waveform.