Apparatus and method for monitoring tissue vitality parameters
First Claim
1. Apparatus for monitoring viability of a tissue element comprising:
- a) at least one light source that illuminates the tissue element from at least one illumination location with at least first illuminating radiation at a first wavelength and second illuminating radiation at a second wavelength;
b) first and second radiation receivers located at first and second distances from the at least one illumination location respectively and at least one radiation detector operatively coupled with said first and second radiation receivers which generates first and second signals respectively responsive to illuminating the tissue element with the first and second illuminating radiations; and
C) a processor that processes the signals to determine first and second tissue viability parameters for the tissue element;
wherein the first and second distances are determined responsive substantially only to the first and second wavelengths and tissue characteristics so that sample depths for the first and second illuminating radiations are substantially equal; and
furtherwherein the first tissue viability parameter is different than the second tissue viability parameter.
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Accused Products
Abstract
Apparatus for monitoring a plurality of tissue viability parameters of a tissue layer element, in which two different illumination sources are used via a common illumination element in contact with the tissue. One illumination source is used for monitoring blood flow rate and optionally flavoprotein concentration, and collection fibers are provided to receive the appropriate radiation from the tissue. The other illuminating radiation is used for monitoring any one of and preferably all of NADH, blood volume and blood oxygenation state of the tissue element, and collection fibers are provided to receive the appropriate radiation from the tissue. In one embodiment, the wavelengths of the two illumination sources are similar, and common collection fibers for the two illuminating radiations are used. In another embodiment, the respective collection fibers are distanced from the illumination point at different distances correlated to the ratio of the first and second illuminating wavelengths.
104 Citations
52 Claims
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1. Apparatus for monitoring viability of a tissue element comprising:
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a) at least one light source that illuminates the tissue element from at least one illumination location with at least first illuminating radiation at a first wavelength and second illuminating radiation at a second wavelength; b) first and second radiation receivers located at first and second distances from the at least one illumination location respectively and at least one radiation detector operatively coupled with said first and second radiation receivers which generates first and second signals respectively responsive to illuminating the tissue element with the first and second illuminating radiations; and C) a processor that processes the signals to determine first and second tissue viability parameters for the tissue element; wherein the first and second distances are determined responsive substantially only to the first and second wavelengths and tissue characteristics so that sample depths for the first and second illuminating radiations are substantially equal; and
furtherwherein the first tissue viability parameter is different than the second tissue viability parameter. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51)
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52. A method for monitoring first and second tissue viability parameters of a tissue element, the method comprising:
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a) illuminating the tissue element from at least one illumination location with first and second illuminating radiations at respectively first and second wavelengths; b) determining first and second distances from the at least one illumination location responsive substantially only to the first and second wavelengths and tissue characteristics so that sample depths for the first and second illuminating radiations for the first and second distances are substantially equal; c) receiving radiations at the first and second distances responsive respectively to illuminating the tissue element with the first and second illuminating radiation, and generating first and second signals responsive thereto; d) determining first and second tissue viability parameters responsive to the first and second signals; and e) outputting an indication of tissue viability based on said determined tissue viability parameters.
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Specification