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Tissue electroperforation for enhanced drug delivery and diagnostic sampling

  • US 7,133,717 B2
  • Filed: 02/28/2001
  • Issued: 11/07/2006
  • Est. Priority Date: 08/25/1999
  • Status: Expired due to Term
First Claim
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1. A method for transporting a molecule through a mammalian barrier membrane of at least one layer of cells comprising the steps of:

  • creating an air gap between an array of treatment electrodes and said membrane;

    ablating said membrane with an electric current from the array of treatment electrodes wherein said electric current forms an electric arc between said treatment electrodes and said membrane; and

    utilizing a driving force to move said molecule through said ablated membrane, wherein said membrane is skin.

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