Ultrasonic surgical instrument for intracorporeal sonodynamic therapy
First Claim
1. An ultrasonic surgical system comprising:
- a housing;
a tubular sheath having a proximal end connected to the housing and a distal end, the tubular sheath defining a longitudinal axis;
a transducer extending distally of the distal end of the tubular sheath;
a membrane extending distally of the distal end of the tubular sheath and having a hollow volume for receiving a pharmaceutical agent and the transducer; and
a pharmaceutical agent delivery system.
3 Assignments
0 Petitions
Accused Products
Abstract
The present invention relates, in general, to ultrasonic surgical instruments and, more particularly, to an intracorporeal ultrasonic surgical instrument for sonodynamic therapy. Disclosed is an ultrasonic surgical system comprising: a generator and an instrument comprising: a housing; a transducer; a semi-permeable membrane; a pharmaceutical agent; and an agent delivery system. The transducer is adapted to convert the electrical energy of the generator into mechanical energy. The pharmaceutical agent, delivered into a chamber of the semi-permeable membrane, is driven through the semi-permeable membrane by the mechanical energy. A method in accordance with the present invention comprises the steps of: providing a surgical instrument comprising: a housing; a transducer connected to the housing; a semi-permeable membrane; a pharmaceutical agent; and an agent delivery system; inserting the surgical instrument into a patient; delivering a drug to the patient; and locally activating the drug with the surgical instrument.
119 Citations
13 Claims
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1. An ultrasonic surgical system comprising:
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a housing;
a tubular sheath having a proximal end connected to the housing and a distal end, the tubular sheath defining a longitudinal axis;
a transducer extending distally of the distal end of the tubular sheath;
a membrane extending distally of the distal end of the tubular sheath and having a hollow volume for receiving a pharmaceutical agent and the transducer; and
a pharmaceutical agent delivery system. - View Dependent Claims (2, 3, 4, 5)
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6. An ultrasonic instrument comprising:
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a housing;
a tubular sheath having a proximal end connected to the housing and a distal end, the tubular sheath defining a longitudinal axis;
a ultrasonic transducer extending distally of the distal end of the tubular sheath;
a membrane having a hollow volume for receiving a pharmaceutical agent and the transducer; and
a pharmaceutical agent delivery system;
wherein said pharmaceutical agent delivery system delivers said pharmaceutical agent into the hollow volume of said membrane; and
whereby said pharmaceutical agent is driven through said membrane by ultrasonic energy delivered from said transducer.
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7. An ultrasonic surgical system comprising:
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a) a generator;
b) an instrument comprising;
i) a housing;
ii) a transducer assembly carried by the housing and adapted to vibrate at an ultrasonic frequency;
iii) a waveguide having a first end adapted to receive ultrasonic vibration from the transducer assembly and a second end operatively connected to an end-effector;
iv) a membrane surrounding said end-effector;
v) a pharmaceutical agent contained in the membrane;
wherein said generator is adapted to provide electrical energy to said transducer assembly;
wherein said transducer is adapted to convert said electrical energy into ultrasonic vibration; and
whereby said pharmaceutical agent is driven through said membrane by said ultrasonic vibration. - View Dependent Claims (8, 9)
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10. An ultrasonic surgical instrument comprising:
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a) a housing;
b) a tubular sheath having a proximal end connected to the housing and a distal end, the tubular sheath defining a longitudinal axis;
c) a transducer extending distally of the distal end of the tubular sheath;
c) a membrane extending distally of the distal end of the tubular sheath and having a hollow volume for receiving a pharmaceutical agent and, the membrane located external and adjacent said transducer; and
d) a pharmaceutical agent. - View Dependent Claims (11, 12, 13)
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Specification