Compositions for use in embolizing blood vessels
First Claim
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1. A composition comprising:
- (a) from about 2.5 to about 8.0 weight percent of a polymer selected from the group consisting of polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid, and mixtures thereof wherein said polymer has a molecular weight of at least 50,000;
(b) from about 10 to about 40 weight percent of a contrast agent wherein said contrast agent is selected from the group consisting of gold, tungsten and platinum powder;
(c) from about 52 to about 87.5 weight percent of dimethylsulfoxide which solubilizes said polymer; and
wherein the weight percent of the polymer, contrast agent and biocompatible solvent is based on the total weight of the complete composition.
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Abstract
Disclosed are compositions suitable for use in embolizing blood vessels which compositions comprise a polymer, a biocompatible solvent and a contrast agent. The polymer is selected from the group consisting of polyacrylonitrile, polyurethane, polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid.
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Citations
9 Claims
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1. A composition comprising:
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(a) from about 2.5 to about 8.0 weight percent of a polymer selected from the group consisting of polyvinylacetate, cellulose acetate butyrate, nitrocellulose and copolymers of urethane/carbonate and copolymers of styrene/maleic acid, and mixtures thereof wherein said polymer has a molecular weight of at least 50,000;
(b) from about 10 to about 40 weight percent of a contrast agent wherein said contrast agent is selected from the group consisting of gold, tungsten and platinum powder;
(c) from about 52 to about 87.5 weight percent of dimethylsulfoxide which solubilizes said polymer; and
wherein the weight percent of the polymer, contrast agent and biocompatible solvent is based on the total weight of the complete composition. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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Specification
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Current AssigneeMirco Therapeutics Incorporated
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Original AssigneeMirco Therapeutics Incorporated
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InventorsWright, James I., Evans, Scott, Greff, Richard J.
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Primary Examiner(s)Webman, Edward J.
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Application NumberUS10/161,606Publication NumberTime in Patent Office1,630 DaysField of Search424/9.41, 424/9.411, 424/423, 424/486, 424/9.4, 424/9.42, 523/105US Class Current424/9.42CPC Class CodesA61K 9/0024 Solid, semi-solid or solidi...A61P 43/00 Drugs for specific purposes...A61P 7/04 Antihaemorrhagics; Procoagu...A61P 9/00 Drugs for disorders of the ...
