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Drug-eluting stent and methods of making the same

  • US 7,144,422 B1
  • Filed: 11/13/2002
  • Issued: 12/05/2006
  • Est. Priority Date: 11/13/2002
  • Status: Expired due to Fees
First Claim
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1. A drug-eluting stent delivery system for controlled release of therapeutic drugs and for delivery of the therapeutic drugs in localized drug therapy in a blood vessel, comprising:

  • a pattern of struts interconnected to form a structure capable of contacting the walls of a body lumen to maintain the patency of the vessel,wherein a polymeric sleeve, fabricated as a prepatterned tube comprising polymer elements, is loaded with at least one therapeutic drug for the release thereof at a treatment site, the polymeric sleeve being attached to at least a portion of an outside surface area of the stent structure andwherein the prepatterning enables the detachment of the polymer elements upon stent expansion,wherein the polymeric sleeve includes a plurality of four-sided, filament strands attached to the surface of the stent, andwherein a barrier coating layer is disposed on three sides of the plurality of four-sided filament strands to enable drug elution along the fourth side.

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