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Pharmaceutical compositions for headache, migraine, nausea and emesis

  • US 7,148,208 B2
  • Filed: 03/05/2003
  • Issued: 12/12/2006
  • Est. Priority Date: 09/05/2000
  • Status: Expired due to Term
First Claim
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1. A method of treating headache or migraine, the method comprising the step of administering to a subject in need of such treatment a therapeutically effective amount of a composition consisting essentially of (a) a compound selected from the group consisting of S-methylisothiouronium methylphosphite;

  • S-methylisothiouronium dimethylphosphate;

    S-ethylisothiouronium metaphosphate;

    S-ethylisothiouronium ethylphosphite;

    S-ethylisothiouronium diethylphosohate;

    S-propylisothiourium propylphosphite;

    S-isopropylisothiouronium metaphosphate;

    S-isopropylisothiouronium isopropylphosphite;

    S-butylisothiouronium dibutylphosphate; and

    S-isobutylisothiouronium isobutylphosphite, and (b) a pharmaceutically acceptable carrier or diluent;

    wherein the composition is formulated as tablets or capsules.

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