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Multi-well rotary synthesizer

  • US 7,150,998 B2
  • Filed: 12/19/2000
  • Issued: 12/19/2006
  • Est. Priority Date: 06/16/1998
  • Status: Expired due to Term
First Claim
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1. A method of selectively and sequentially dispensing a plurality of reagent solutions to a plurality of vials divided into a first bank of vials and a second bank of vials and selectively purging material from the first bank of vials and the second bank of vials, comprising:

  • a. providing a multi-well synthesizer including a controller, a plurality of vials divided into a first bank of vials and a second bank of vials, a plurality of valves for delivering reagent solutions to selective vials, a first drain corresponding to the first bank of vials, a second drain corresponding to the second bank of vials and a waste tube;

    b. dispensing one or more of the plurality of reagent solutions through a selective one of the plurality of valves to a selective one or more of the plurality of vials, to perform synthesis within the selective one or more of the plurality of vials;

    c. coupling a waste tube to a selective one of the first drain and the second drain within a purging system by moving the waste tube to the selective one of the first drain and the second drain until the waste tube is coupled with the selective one of the first drain and the second drain; and

    d. purging material from the selected one of the first bank of vials and the second bank of vials through the purging system.

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