Implantable substrate coated with a macromer having free radical polymerizable substituents
First Claim
1. A substrate comprising a surface having a polymeric coating thereon formed by free radical polymerization of a biocompatible, substantially water soluble macromer comprising at least two free radical polymerizable substituents,wherein the coating further comprises one or more polysaccharideswherein the substrate is an implantable material.
1 Assignment
0 Petitions
Accused Products
Abstract
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.
-
Citations
8 Claims
-
1. A substrate comprising a surface having a polymeric coating thereon formed by free radical polymerization of a biocompatible, substantially water soluble macromer comprising at least two free radical polymerizable substituents,
wherein the coating further comprises one or more polysaccharides wherein the substrate is an implantable material.
Specification