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Apparatus and methods for cleaning and priming droplet dispensing devices

  • US 7,153,689 B2
  • Filed: 08/01/2002
  • Issued: 12/26/2006
  • Est. Priority Date: 08/01/2002
  • Status: Expired due to Fees
First Claim
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1. A method for cleaning and priming a droplet dispensing device for dispensing a fluid reagent for synthesis, said dispensing device comprising a plurality of nozzles aligned in at least one row, said method comprising:

  • (a) sealingly engaging a dispensing surface of said dispensing device comprising said nozzles to form a chamber adjacent said dispensing surface,(b) introducing a wash fluid into said chamber and removing said wash fluid from said chamber, and(c) applying a vacuum individually to at least a portion of the plurality of said nozzles within said chamber wherein the vacuum is sufficient to prime said portion of the plurality of said nozzles with the fluid reagent to be dispensed and wherein the vacuum is applied to said portion of the plurality of said nozzles by means of individual vacuum sources.

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