Treatment of movement disorders with drug therapy
First Claim
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1. A method of treating a patient with a movement disorder, comprising:
- providing at least one implantable stimulator for controlling delivery of at least one stimulus via at least one infusion outlet, wherein the at least one stimulus comprises stimulation via at least one drug delivered through the at least one outlet;
implanting the at least one stimulator entirely or substantially in the carotid sheath; and
using the stimulator, applying the at least one stimulus to at least one vagus nerve in order to, at least in part, alleviate the movement disorder of the patient being treated.
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Abstract
Introducing one or more stimulating drugs to the vagus nerve and/or one or more branches of the vagus nerve to treat movement disorders uses at least one implantable system control unit (SCU) with an implantable pump with at least one infusion outlet. Optional electrical stimulation may additionally be supplied by an implantable signal/pulse generator (IPG) with one or more electrodes. In certain embodiments, a single SCU provides one or more stimulating drugs and the optional electrical stimulation. In some embodiments, one or more sensed conditions are used to adjust stimulation parameters.
312 Citations
21 Claims
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1. A method of treating a patient with a movement disorder, comprising:
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providing at least one implantable stimulator for controlling delivery of at least one stimulus via at least one infusion outlet, wherein the at least one stimulus comprises stimulation via at least one drug delivered through the at least one outlet; implanting the at least one stimulator entirely or substantially in the carotid sheath; and using the stimulator, applying the at least one stimulus to at least one vagus nerve in order to, at least in part, alleviate the movement disorder of the patient being treated. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A method of treating a patient with a movement disorder, comprising:
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providing at least one system control unit; providing at least one catheter connected to the at least one system control unit, which catheter includes at least one discharge portion; implanting the at least one catheter discharge portion adjacent to at least one vagus nerve to be stimulated; implanting the at least one system control unit; and delivering at least one drug to the at least one vagus nerve, thereby affecting a movement disorder in order to at, least in part, alleviate the movement disorder of the patient being treated. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification