Method and system for myocardial infarction repair
First Claim
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1. An implantable system comprising:
- (a) a cell repopulation source of stem cells for a patient'"'"'s myocardium; and
(b) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient'"'"'s myocardium, wherein the electrical stimulation device provides burst stimulation.
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Abstract
An implantable system is provided that includes: a cell repopulation source comprising genetic material, undifferentiated and/or differentiated contractile cells, or a combination thereof capable of forming new contractile tissue in and/or near an infarct zone of a patient'"'"'s myocardium; and an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient'"'"'s myocardium or otherwise damaged or diseased myocardial tissue.
74 Citations
29 Claims
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1. An implantable system comprising:
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(a) a cell repopulation source of stem cells for a patient'"'"'s myocardium; and (b) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the infarct zone of the patient'"'"'s myocardium, wherein the electrical stimulation device provides burst stimulation. - View Dependent Claims (11, 19, 20, 21)
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2. A method of repairing the myocardium of a patient, the method comprising:
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(a) providing an implantable system comprising; (i) a cell repopulation source comprising genetic material, stem cells, or a combination thereof, capable of forming new contractile tissue in and/or near an infarct zone of a patient'"'"'s myocardium; and (ii) an electrical stimulation device for electrically stimulating the new contractile tissue in and/or near the damaaed or diseased myocardial tissue; (b) implanting the cell repopulation source into and/or near damaged or diseased myocardial tissue of a patient; (c) allowing sufficient time for new contractile tissue to form from the cell repopulation source; and (d) electrically stimulating the new contractile tissue. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9)
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10. An implantable system comprising:
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(a) a cell repopulation source of stem cells capable of forming new contractile tissue in and/or near damaged or diseased myocardial tissue; and (b) an electrical stimulation device for electrically stimulating the new contractile tissue formed in the myocardial tissue. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 22, 23, 24, 25, 26, 27, 28, 29)
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Specification