Infrared monitor and control for vapor hydrogen peroxide processing techniques

• US 7,157,045 B2
• Filed: 07/09/2002
• Issued: 01/02/2007
• Est. Priority Date: 07/10/2001
• Status: Active Grant

• Current Assignee: American Sterilizer Company (Steris Corporation)
• Original Assignee: Steris Corporation
• Inventors: McVey, Iain F.
• Primary Examiner(s): JASTRZAB, KRISANNE MARIE
• Application Number:
  US10/191,821
• Publication Number:
  US 20030021724A1
• Time in Patent Office: 1,638 Days
• Field of Search: 422/62, 422/3, 422/4, 422/28, 422/105, 250/339.12, 250/339.13, 250/343
• US Class Current: 422/3
• CPC Class Codes: A61L 2/208 Hydrogen peroxide
• CPC Class Codes: A61L 2/24 Apparatus using programmed or automatic operation
• CPC Class Codes: A61L 2/28 Devices for testing the effectiveness or completeness of sterilisation, e.g. indicators which change colour apparatus involving enzymes or microorganisms C12M1/34; methods involving enzymes or microorganisms C12Q1/00
• CPC Class Codes: A61L 2202/122 Chambers for sterilisation
• CPC Class Codes: A61L 2202/14 Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
• CPC Class Codes: A61L 9/02 using substances evaporated in the air by heating or combustion
• CPC Class Codes: G01N 2021/3148 using three or more wavelengths
• CPC Class Codes: G01N 21/3504 for analysing gases, e.g. multi-gas analysis
• CPC Class Codes: G01N 33/006 avoiding interference of water vapour with the gas to be measured

Abstract

A vaporizer (14) supplies hydrogen peroxide and water vapor to a high level disinfection or sterilization region (20). Mid-infrared light detectors (32) detect light in the mid-infrared range which has traversed a region of the treatment chamber in a first narrow spectrum centered at 8,000 nanometers which is absorbed by the hydrogen peroxide vapor, a second narrow spectrum which is absorbed by the water vapor, and a third spectrum that is absorbed by neither the hydrogen peroxide vapor nor the water vapor. From these measurements, an absorbance or transmittance is determined (40) from which the concentrations of hydrogen peroxide and water vapor are determined (42). Monitored temperature (44) and the determined concentrations are converted into a percent saturation (54). The supply of hydrogen peroxide and water vapor to the chamber is controlled (60) in accordance with the determined percent saturation.

Claims

1. A peroxy vapor system including:

a light source which supplies light with at least a component in the mid-infrared range;

a detector which individually detects mid-infrared range light in (a) a first narrow mid-infrared spectrum absorbed by peroxy vapor and not absorbed by the carrier vapor, (b) a second narrow mid-infrared spectrum absorbed by a carrier vapor and not absorbed by the peroxy vapor, and (c) a third mid-infrared spectrum absorbed by neither the peroxy vapor nor the carrier vapor; and

a processor for determining at least a concentration of the peroxy vapor from the detected light only in the mid-infrared range.

2. The system of claim 1 further including a source of hydrogen peroxide vapor and includes water vapor.

4. The system as set forth in claim 1 wherein the concentration determining processor includes:

a means for determining at least one of (a) an absorbance of light in the first and second spectrums and (b) a transmittance of light in the first and second spectrums; and

a means for converting the determined absorbance or transmittance into a concentration of the peroxy vapor and a concentration of the carrier vapor.

5. The system as set forth in claim 1 further including:

a temperature sensor for sensing temperature; and

a percent saturation means for determining a percent saturation from the sensed temperature, the peroxy vapor concentration, and the carrier vapor concentration.

6. The system as set forth in claim 5 wherein the percent saturation means includes:

a means for converting concentrations of the peroxy vapor and the carrier vapor into partial vapor pressures;

a means for combining the partial vapor pressures; and

a means for converting the partial vapor pressure, the temperature, and the peroxy and carrier vapor concentrations into the percent saturation.

7. The system as set forth in claim 6 wherein at least one of the concentration determining processor, the vapor pressure determining means, and the saturation determining means includes a look-up table.

8. The system as set forth in claim 5 further including:

a source of a liquid peroxy and carrier mixture;

a vaporizer for vaporizing the liquid mixture to form the peroxy vapor and the carrier vapor;

a comparing means for comparing the determined percent saturation with a preselected percent saturation; and

,

a control means for controlling vaporization of the liquid mixture in accordance with the comparison of the determined and preselected percent saturation.

9. The system as set forth in claim 8 wherein the control means is configured to control vaporization to maintain the percent saturation in a range of 95–

99percent saturation.

10. The system as set forth in claim 8 further including:

an integrating means for integrating the determined concentration of peroxy vapor over time; and

,

an end of cycle means for terminating generation of the peroxy vapor in accordance with the integrated concentration over time.

11. The system as set forth in claim 5 further including:

a source of a liquid peroxy and carrier mixture; and

,

a vaporizer for vaporizing the liquid mixture to form the peroxy vapor and the carrier vapor;

a control for controlling vaporization of the liquid mixture in accordance with at least one of the peroxy vapor concentration and the percent saturation.

13. The system as set forth in claim 11, further including:

a comparing means for comparing the determined peroxy vapor concentration with a minimum peroxy vapor concentration.

3. A peroxy vapor system including:

a light source which supplies light with at least a component in the mid-infrared range;

a detector which individually detects mid-infrared range light in (a) a first narrow spectrum which is centered at about 8,000 nanometers and is absorbed by peroxy vapor, (b) a second narrow spectrum absorbed by a carrier vapor, and (c) a third spectrum absorbed by neither the peroxy vapor nor the carrier vapor;

a processor for determining at least a concentration of the peroxy vapor from the detected light in the mid-infrared range.

12. A peroxy vapor system including:

a treatment region;

a means for generating peroxy vapor and supplying the peroxy vapor to the treatment region;

a light source which supplies light to the treatment region with at least a component in the mid-infrared range;

a detector which individually detects mid-infrared range light that has traversed at least a portion of the first treatment region in (a) a first narrow spectrum absorbed by peroxy vapor, (b) a second narrow spectrum absorbed by a carrier vapor, and (c) a third spectrum absorbed by neither the peroxy vapor nor the carrier vapor;

a processor for determining at least a concentration of the peroxy vapor from the detected light in the mid-infrared range;

an integrating means for integrating the determined concentration of peroxy vapor over time; and

,

an end of cycle means for terminating generation of the peroxy vapor in accordance with the integrated concentration over time.

14. A disinfection or sterilization system comprising:

a treatment chamber;

a source of aqueous peroxy solution;

a vaporizer for vaporizing the aqueous peroxy solution to form a peroxy vapor and a water vapor and for supplying the peroxy and water vapors to the treatment chamber;

a light source which projects a beam of light in a mid-infrared range through the peroxy and water vapors;

a mid-infrared light detector which detects (a) a first narrow spectrum absorbed by the peroxy vapor and not the water vapor, (b) a second narrow spectrum absorbed by the water vapor and not the peroxy vapor, and (c) a third spectrum absorbed by neither the peroxy nor the water vapor;

an absorbance/transmittance processor which converts the detected first, second, and third spectrum light into one of (a) absorbance values indicative of mid infrared light absorbed by the peroxy and water vapors and (b) transmittance values indicative of mid-infrared light transmitted through the peroxy and water vapors;

a processor which converts the determined absorbance/transmittance values into a concentration of the peroxy vapor and a concentration of the water vapor;

a temperature monitor for monitoring temperature in the treatment chamber;

a percent saturation processor which converts the concentration of the peroxy vapor, the concentration of the water vapor, and the temperature into an indication of a percent saturation in the treatment chamber; and

,

a control processor which controls the generation of peroxy and water vapor in accordance with the determined percent saturation.

15. The system as set forth in claim 14 wherein the saturation processor includes:

a means for determining partial vapor pressures of the peroxy vapor and the water vapor from the determined peroxy vapor concentration and the determined water vapor concentration;

a means for combining the partial vapor pressures to form a total vapor pressure; and

a look-up table for determining the percent saturation from the monitored temperature, the peroxy and water vapor concentrations, and the total vapor pressure.

16. The system as set forth in claim 14 wherein the control processor includes:

a means for comparing the determined percent saturation with a preselected percent saturation; and

a means for controlling the generation of peroxy and water vapor in accordance with the percent saturation comparison.

17. The system as set forth in claim 16 wherein the control processor further includes:

an integrator for integrating the concentration of peroxy vapor over time; and

,

a means for ending disinfection or sterilization cycle in accordance with the integrated concentration of peroxy vapor.

18. The system as set forth in claim 14 wherein the peroxy vapor includes hydrogen peroxide vapor.

19. A peroxy vapor method including:

projecting light in a mid-infrared range through a monitored region;

detecting mid-infrared light in (a) a first narrow spectrum absorbed by the peroxy vapor, (b) a second narrow spectrum absorbed by a carrier vapor, and (c) a third spectrum absorbed by neither the peroxy vapor nor the carrier vapor; and

,

determining at least a concentration of the peroxy vapor from the light detected in the mid-infrared range.

20. The method as set forth in claim 19 wherein the peroxy vapor includes hydrogen peroxide and the carrier vapor includes water vapor.

21. The method as set forth in claim 19 wherein the first narrow spectrum is centered about 8,000 nanometers.

22. The method as set forth in claim 19 further including:

converting the determined spectrums into one of absorbance and transmittance of mid infrared light through the peroxy vapor and the carrier vapor and converting the determined one of the absorbance and transmittance into the concentration of the peroxy vapor and a concentration of the carrier vapor.

23. The method as set forth in claim 19 further including:

sensing a temperature in the monitored region; and

determining a percent saturation of vapor in the monitored region from the sensed temperature and the peroxy concentration and a carrier vapor concentration.

24. The method as set forth in claim 23 wherein the step of determining the percent saturation further includes:

converting the concentrations of the peroxy vapor and the carrier vapor into partial vapor pressures of the peroxy and carrier vapors;

combining the partial vapor pressures; and

,

determining the percent saturation from the monitored temperature and the total vapor pressure.

25. The method as set forth in claim 23 further including:

supplying peroxy and carrier vapor to the monitored region; and

,

controlling the supplying of peroxy and carrier gas vapor in accordance with the determined percent saturation.

26. The method as set forth in claim 25 wherein the supply of peroxy and carrier vapor is controlled to maintain the peroxy and carrier gas vapor in the monitored region between 95–

99% of saturation.

27. The method as set forth in claim 25 further including:

integrating the determined peroxy vapor concentration with time; and

terminating supplying the peroxy and carrier vapor to the monitored region in accordance with the integrated concentration.

28. The method as set forth in claim 20 wherein the first spectrum is absorbed by the hydrogen peroxide vapor and is not absorbed by the water vapor and the second spectrum is absorbed by the water vapor and not by the hydrogen vapor.