Method and device for sensing and mapping temperature profile of a hollow body organ

• US 7,160,255 B2
• Filed: 05/30/2003
• Issued: 01/09/2007
• Est. Priority Date: 07/12/2001
• Status: Expired due to Fees

• Current Assignee: Vahid Saadat
• Original Assignee: Vahid Saadat
• Inventors: Saadat, Vahid
• Primary Examiner(s): MARMOR II, CHARLES ALAN
• Application Number:
  US10/452,409
• Publication Number:
  US 20040059235A1
• Time in Patent Office: 1,320 Days
• Field of Search: 600/373, 600/381, 600433-435, 600/474, 600/547, 600/549, 600/585, 600/38, 604/528, 604/530, 374/148, 374/166, 374/179
• US Class Current: 600/549
• CPC Class Codes: A61B 5/015 By temperature mapping of body part
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter

Abstract

A method and device for sensing the temperature profile of a hollow body organ includes a catheter and a hollow guidewire carrying a thermal sensor. The guidewire is configured to displace the thermal sensor radially relative to the catheter when unconstrained and can be rotated about the longitudinal axis of the catheter. When constrained within the catheter, the guidewire can be advanced to a region of interest in hollow body organ. The catheter can be withdrawn, leaving the guidewire in place in an expanded configuration wherein the thermal sensor contacts the inner wall of the hollow body organ. The guidewire is moveable to sense the temperature at multiple locations. The thermal sensor can be replaced with an electrode for sensing the impedance profile of the hollow body organ.

Claims

1. A device for sensing a temperature profile of a hollow body organ, comprising:

a guidewire having a tubular helix structure continuous along an entire length of the guidewire, and sized for intravascular insertion and adapted to be disposed in a relaxed configuration externally of a catheter where a distal tip of the guidewire is laterally displaced relative to a longitudinal axis of the guidewire, and in a contracted configuration internally of the catheter; and

a temperature sensor connected to the distal tip of the guidewire and moveable therewith, the temperature sensor being adapted to be displaced laterally with the guidewire when in the relaxed configuration, wherein the temperature sensor is further adapted to be rotated about the longitudinal axis via the guidewire.

2. The device of claim 1, wherein the guidewire comprises a material having martensitic transformation properties.

3. The device of claim 2, wherein the guidewire comprises Nitinol.

4. The device of claim 1, wherein the guidewire comprises an elastic material.

5. The device of claim 4, wherein the guidewire comprises spring steel.

6. The device of claim 1, wherein the temperature sensor is a thermocouple.

7. The device of claim 6, wherein the temperature sensor comprises one leg of the thermocouple and the guidewire comprises another leg of the thermocouple.

8. The device of claim 1, wherein the temperature sensor is a thermistor.

9. The device of claim 1, wherein the temperature sensor comprises a thermochromic material.

10. The device of claim 9, wherein the thermochromic material is in thermal contact with a lumen of the guidewire.

11. The device of claim 10, wherein the temperature sensor further includes an optical probe for sensing a color of the thermochromic material.

12. The device of claim 11, wherein the optical probe includes an illumination device for illuminating a region of interest of the guidewire.

13. The device of claim 12, wherein the optical probe includes a sensing device for sensing reflected radiation from the thermochromic material.

14. The device of claim 13, wherein the reflected radiation is in the visible spectrum.

15. The device of claim 13, wherein the reflected radiation is in the infrared spectrum.

16. The device of claim 13, wherein the reflected radiation is in the ultraviolet spectrum.

17. The device of claim 1, wherein the temperature sensor is adapted for rotational displacement about the longitudinal axis of the catheter while in contact with the body organ.

18. The device of claim 1, further comprising a catheter having a longitudinal axis within which the guidewire is disposed.

19. A device for sensing an impedance profile of a body organ, comprising:

a catheter having a longitudinal axis;

a guidewire having a tubular helix structure continuous along an entire length of the guidewire, and sized for intravascular insertion and being adapted to be disposed in a relaxed configuration externally of the catheter where a distal tip of the guidewire is laterally displaced relative to a longitudinal axis of the guidewire, and in a contracted configuration internally of the catheter; and

an electrode connected to the distal tip of the guidewire and moveable therewith, the electrode being adapted to be displaced laterally with the guidewire when in the relaxed configuration, wherein the electrode is further adapted to be rotated about the longitudinal axis via the guidewire.

20. A method for sensing a temperature profile of a hollow body organ, comprising the steps of:

providing a guidewire having a tubular helix structure which is adapted to be disposed in a relaxed configuration externally of a catheter where a distal tip of the guidewire is laterally displaced relative to a longitudinal axis of the guidewire, and in a contracted configuration internally of the catheter;

providing at least one thermal sensor connected to the distal tip of the guidewire and moveable therewith, the at least one thermal sensor being adapted to be displaced laterally with the guidewire when in the relaxed configuration;

advancing the guidewire to a region of interest in a hollow body organ;

relaxing the guidewire within the hollow body organ such that the at least one thermal sensor is displaced laterally in contact with the hollow body organ; and

rotating the at least one thermal sensor about the longitudinal axis.

21. The method of claim 20, wherein the guidewire comprises a material having martensitic transformation properties.

22. The method of claim 21, wherein the guidewire comprises Nitinol.

23. The method of claim 20, wherein the guidewire comprises an elastic material.

24. The method of claim 23, wherein the guidewire comprises spring steel.

25. The method of claim 20, wherein the at least one thermal sensor comprises a thermocouple.

26. The method of claim 25, wherein the at least one thermal sensor comprises one leg of the thermocouple and the guidewire comprises another leg of the thermocouple.

27. The method of claim 20, wherein the at least one thermal sensor comprises a thermistor.

28. The method of claim 20, wherein the at least one thermal sensor comprises a thermochromic material.

29. The method of claim 28, wherein the thermochromic material is in thermal contact with a lumen of the guidewire.

30. The method of claim 29, wherein the at least one thermal sensor further includes an optical probe for sensing a color of the thermochromic material.

31. The method of claim 30, wherein the optical probe includes an illumination device for illuminating a region of interest of the guidewire.

32. The method of claim 31, wherein the optical probe includes a sensing device for sensing reflected radiation from the thermochromic material.

33. The method of claim 32, wherein the reflected radiation is in the visible spectrum.

34. The method of claim 32, wherein the reflected radiation is in the infrared spectrum.

35. The method of claim 32, wherein the reflected radiation is in the ultraviolet spectrum.

36. The method of claim 20, further comprising sensing the temperature of the hollow body organ while rotating the at least one thermal sensor.

37. The method of claim 20, wherein the rotation is continuous.

38. The method of claim 20, wherein the rotation is continual.

39. The method of claim 20, further comprising providing a catheter within which the guidewire is disposed prior to advancing the guidewire to the region of interest.

40. The method of claim 39, further comprising contracting the guidewire elastically and constraining the guidewire within the lumen of the catheter prior to advancing the guidewire to the region of interest.

41. The method of claim 40, further comprising withdrawing the catheter while securing the guidewire against substantial longitudinal movement relative to the hollow body organ, whereby the guidewire relaxes prior to sensing the temperature of the hollow body organ.