Reinforced small intestinal submucosa
First Claim
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1. A bioprosthetic device comprising:
- a sheet of small intestine submucosa; and
a sheet of bioabsorbable synthetic mesh coupled to the small intestine submucosa, wherein the sheet of synthetic mesh has a rate of absorption that is slower than a rate of absorption of the sheet of small intestine submucosa.
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Abstract
Bioprosthetic devices for soft tissue attachment, reinforcement, or construction are provided. The devices comprise a sheet of naturally occurring extracellular matrix and a sheet of synthetic mesh coupled to the naturally occurring extracellular matrix portion.
461 Citations
14 Claims
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1. A bioprosthetic device comprising:
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a sheet of small intestine submucosa; and a sheet of bioabsorbable synthetic mesh coupled to the small intestine submucosa, wherein the sheet of synthetic mesh has a rate of absorption that is slower than a rate of absorption of the sheet of small intestine submucosa. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
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11. A bioprosthetic device comprising:
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multiple sheets of naturally occurring extracellular matrix; and multiple sheets of synthetic mesh coupled to the naturally occurring extracellular matrix, wherein the bioprosthetic device comprises a stack of the sheets of naturally occurring extracellular matrix separated by the sheets of synthetic mesh.
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12. A bioprosthetic comprising:
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a top sheet of small intestinal submucosa comprising multiple small intestine submucosalayers, the top sheet having a first surface area, a bottom sheet of small intestine submucosa comprising multiple small intestine submucosa layers, the bottom sheet having a second surface area, wherein the first area and second area are the same; and a bioabsorbable mesh device having a third surface area, the mesh device coupled to and positioned to lie between the top and bottom sheets of small intestine submucosa, wherein the sheet of synthetic mesh has a rate of absorption that is slower than a rate of absorption of the sheet of naturally occurring extracellular matrix. - View Dependent Claims (13, 14)
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Specification