Methods for increasing schwann cell survival
First Claim
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1. A method for increasing survival of Schwann cells, comprising administering an effective amount of a compound selected from the group consisting of a deprenyl compound, N-acetyl cysteine and IGF-1, to a patient such that survival of Schwann cells is increased.
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Abstract
Methods for increasing Schwann cell survival are disclosed. The methods of the invention are useful for the treatment of conditions such as peripheral neuropathies, including diabetic neuropathies.
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26 Claims
- 1. A method for increasing survival of Schwann cells, comprising administering an effective amount of a compound selected from the group consisting of a deprenyl compound, N-acetyl cysteine and IGF-1, to a patient such that survival of Schwann cells is increased.
- 18. A method for inhibiting peripheral neuropathy, comprising administering to a patient an effective amount of a compound selected from the group consisting of a deprenyl compound, N-acetyl cysteine and IGF-1, such that peripheral neuropathy is inhibited.
- 22. A method for increasing Schwann cell survival in a patient, comprising contacting a Schwann cell with a compound selected from the group consisting of a deprenyl compound, N-acetyl cysteine and IGF-1, such that Schwann cell survival increases.
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26. A method for treating peripheral neuropathy, comprising administering to a patient an effective amount of a compound selected from the group consisting of a deprenyl compound, N-acetyl cysteine and IGF-1, such that peripheral neuropathy is treated.
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