Synchronized atrial anti-tachy pacing system and method

• US 7,162,300 B2
• Filed: 05/12/2003
• Issued: 01/09/2007
• Est. Priority Date: 01/13/2003
• Status: Expired due to Fees

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Groen, Joanneke Gerrigje, Begemann, Malcom J., van Groeningen, Chritianus J. J. E.
• Primary Examiner(s): Manuel; George
• Application Number:
  US10/435,071
• Publication Number:
  US 20040138715A1
• Time in Patent Office: 1,338 Days
• Field of Search: 607/9, 607 11- 16, 600/510
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3624 occurring in the atrium, i.e. atrial tachycardia

Abstract

A system and method for an implantable cardiac pacing device provide for delivery of anti-tachycardia pacing of the atrium upon detection of atrial tachycardia combined with automatic re-synchronization of ventricular pacing directly following the last atrial pulse of the anti-tachycardia scheme. At the onset of delivery of the ATP train or like scheme of ATP, an appropriate ventricular pacing interval is calculated to enable asynchronous pacing of the ventricle during the ATP and synchronous delivery of the next ventricular pulse at a delay following the end of the ATP train. Upon determination of AT, an algorithm is used to calculate if a ventricular pacing interval can be found that meets maximum and minimum pacing criteria and also provides that the next ventricular pace pulse following the end of the ATP train will follow the last atrial pulse of the train by a suitable AV delay. If such a suitable pacing interval is found, the ventricular pacing interval is set to a temporary value and the train is delivered. If such a pacing interval cannot be initially determined the system waits for one more atrial sense and then repeats the determination to find such a suitable ventricular pacing interval.

Claims

1. An implantable cardiac pacing device, comprising:

ventricular pacing means for pacing the patient'"'"'s ventricle with pace pulses at an adaptable pacing interval;

AT means for determining AT and for determining the timing of the start of an AT episode;

train means for delivering an ATP train in fixed relation to said AT start;

algorithm means activated at said start of an AT episode for determining if ventricular pace pulses can be delivered following a said AT start with an adapted pacing interval whereby a synchronized ventricular pace pulse will be delivered synchronized to the last atrial pulse of a said AT train that has been delivered, said determining including determining said adapted pacing interval subject to predetermined pacing interval and AV criteria;

temporary means for temporarily changing the pacing interval to said adapted value when it is determined that a said adapted pacing interval can be determined;

wait means operative if said algorithm means determines that a said synchronized pace pulse cannot be delivered for activating said algorithm means after waiting for sensing of another atrial beat; and

initiating means for initiating said train means to deliver a said ATP train upon a said pacing interval determination that a synchronized ventricular pace pulse can be delivered.

2. The device as described in claim 1, comprising rhythm means for determining whether AT remains present following delivery of a said ATP train and a said synchronized ventricular pulse.

3. The device as described in claim 1, comprising repeat means for repeating the operation of said algorithm means when AT is determined to be present following delivery of a said ATP train.

4. The device as described in claim 1, comprising storage means for storing criteria relating to maximum and minimum values of pacing interval and maximum and minimum values of AV delay.

5. The device as described in claim 1, comprising revert means operative after delivery of a synchronized pulse for changing said ventricular pacing interval back to the value it had prior to delivery of a said ATP train.

6. The device as described in claim 1, wherein said temporary means controls said ventricular pacing means to deliver ventricular pace pulses asynchronously at said temporary pacing interval during said ATP train duration.

7. The device as described in claim 1, wherein said algorithm means comprises second storage means for storing the duration of said ATP train and means for determining the time interval from the last ventricular pace pulse before AT to the start of said ATP train.

8. The device as described in claim 7, comprising calculation means for calculating when said adapted interval can suitably be the same as the pacing interval before delivery of said ATP train.

9. The device as described in claim 7, wherein said calculation means calculates when said adapted interval can suitably be longer than the pacing interval before delivery of said ATP train.

10. An implantable cardiac pacing system, comprising:

ventricular pacing means for pacing the patient'"'"'s ventricle with pace pulses delivered at an adaptable pacing interval;

AT means for determining the occurrence of AT and for determining a designated time of start of AT;

train means for delivering an ATP train of atrial pulses in fixed relation to said AT start; and

adapting means for adapting the pacing interval of said ventricular pacing means so that the next ventricular pace pulse delivered after the end of said ATP train is re-synchronized to the last atrial pulse of said ATP train;

wherein said adapting means comprises delay means for determining when a suitable pacing interval cannot be calculated at the time of AT start and for then delaying delivery of a said ATP train and calculation of a suitable adapted pacing interval by one atrial cycle.

11. The system as described in claim 10, wherein said train means comprises means for delivering a sequence of atrial pulses at a constant ATP interval and for delivering the first of said train pulses at said ATP interval following said AT start.

12. The system as described in claim 10, wherein said adapting means comprises storage means for storing AV_min and AV_max allowable values of AV delay and sync means for determining a ventricular pacing interval whereby ventricular pace pulses are delivered asynchronously during the duration of said ATP train and the re-synchronized ventricular pace pulse delivered after the conclusion of said ATP train is timed to follow the last atrial pulse of said train by an interval within the range of AV_min to AV_max.

13. The system as described in claim 12, wherein said adapting means comprises algorithm means for determining if the ventricular pacing interval prior to AT start can be maintained and provide for said re-synchronized pulse.

14. The system as described in claim 12, wherein said algorithm means comprises means for determining when the ventricular pacing interval can be set to a shorter value.

15. The system as described in claim 12, wherein said algorithm means comprises means for determining when the ventricular pacing interval can be set to a longer value.

16. The system as described in claim 10, wherein said train means comprises fixed sequence means for delivering a predetermined group of atrial pulses in a fixed sequence, and wherein said adapting means comprises train storage means for storing the duration of said fixed sequence of pulses.

17. The system as described in claim 10, comprising detection means operative following delivery of a said train for detecting if AT remains, and repeat means for repeating the operation of said train means and said adapting means if AT remains.

18. The system as described in claim 17, comprising reset means for resetting the ventricular pacing interval to its former value following delivery of said re-synchronizing pulse.

19. A method of dual chamber pacing, comprising:

determining the existence of atrial tachycardia (AT) and designating a start of said AT;

storing data concerning an ATP sequence of atrial pulses to be delivered to interrupt an AT;

determining a temporary pacing interval for asynchronously pacing the ventricle after start of AT, wherein said temporary pacing interval meets predetermined rate criteria and is calculated to provide for re-synchronization after the last atrial pulse of said ATP sequence;

delivering said ATP sequence in timed relation to said AT start;

delivering ventricular pace pulses at said temporary pacing interval through the duration of said sequence;

delivering the next ventricular pulse following the end of said sequence at said temporary pacing interval, whereby said next ventricular pulse is synchronized to the last atrial pulse of said ATP sequence, thereby re-synchronizing ventricular pacing; and

determining when a temporary pacing interval cannot be calculated that meets predetermined criteria, delaying delivery of said ATP sequence, and sensing the next atrial beat.

20. The method as described in claim 19, comprising storing the ventricular pacing interval just before AT start, and re-setting said ventricular pacing interval to said stored pacing interval after delivery of said next re-synchronizing pulse.

21. The method as described in claim 19, comprising delivering said sequence of atrial pulses at a constant interval and delivering the first of said sequence of pulses at said constant interval following said AT start.

22. The method as described in claim 19, comprising storing AV_min and AV_max allowable values of AV delay, and wherein said determining comprises determining that said next ventricular pulse is delivered within AV_min to AV_max after said last atrial pulse of said ATP sequence.

23. The method as described in claim 22, comprising storing values of minimum and maximum pacing intervals, and wherein said determining comprises determining that said temporary pacing interval is within the range of AV_min to AV_max.

24. The method as described in claim 19, comprising determining the current pacing interval just before AT start and determining when the temporary pacing interval can be set to a value shorter than said current pacing interval.

25. The method as described in claim 19, comprising determining the current pacing interval just before AT start and determining when the temporary pacing interval can be set to a value equal to said current pacing interval.

26. The method as described in claim 19, comprising determining the current pacing interval just before AT start and determining when the temporary pacing interval can be set to a value longer than said current pacing interval.

27. The method as described in claim 19, comprising detecting if AT remains after delivering a said ATP sequence, and repeating said determining step after sensing said next atrial beat.

28. A pacing system for detecting and treating atrial tachycardia in a patient and re-synchronizing ventricular pacing of the patient directly after the tachycardia treatment, comprising:

AT means for delivering an ATP train of a fixed sequence of pulses to the patient'"'"'s atrium;

temporary means for delivering asynchronous ventricular pacing pulses at a temporary pacing interval to the patient'"'"'s ventricle during said ATP train and for the next ventricular pacing pulse after the last pulse of said sequence, whereby said next ventricular pacing pulse is synchronously timed with respect to said last sequence pulse, wherein said temporary means comprises calculating means for calculating said temporary pacing interval;

storage means for storing pacing interval criteria and AV criteria; and

delay means for delaying the operation of said AT means and said temporary means until said calculating means can calculate a temporary pacing interval that meets said stored pacing interval and AV criteria

wherein said delay means initiates operation of said AT means and said calculating means after one additional atrial beat is sensed.

29. The system as described in claim 28, wherein said temporary means comprises storage means for storing a range of acceptable AV delay values and said calculating means comprises means for calculating said temporary pacing interval so that said next ventricular pacing pulse is delivered at a delay following said last pulse, where said delay is within said range.

30. The system as described in claim 29, wherein said temporary means comprises limit means for limiting said temporary pacing interval to a value within a predetermined range of pacing intervals.

31. The system as described in claim 28, wherein said calculating means comprises selection means for selecting a pacing interval from among intervals that are longer and shorter than the pacing interval at time of detecting atrial tachycardia.

32. A method of optimising synchronous pacing of a patient following an episode of atrial tachycardia, comprising:

detecting atrial tachycardia and preparing delivery of an ATP sequence to the patient'"'"'s atrium;

calculating a temporary pacing interval for asynchronous pacing of the patient'"'"'s ventricle while said ATP sequence is delivered and which will enable delivery of a next ventricular pace pulse after the end of said sequence that is synchronously timed in relation to the end of the ATP sequence; and

delivering said ATP sequence and asynchronously pacing the ventricle at said temporary pacing interval through and including delivery of a synchronous pace pulse to the ventricle after the end of said sequence;

wherein said calculating comprises calculating a pacing interval that is between a predetermined minimum value and a predetermined maximum value and determining that said synchronous pace pulse is delivered within a predetermined AV range following the end of said ATP sequence;

storing values of AV max and AV min; and

delivering said synchronous pace pulse at an AV delay after the end of said ATP sequence that is no less than AV min and no more than AV max.

33. The method as described in claim 32, comprising storing a current pacing interval before detection of atrial tachycardia and resuming synchronous pacing with said current pacing interval after delivery of said synchronous pace pulse.

34. The method as described in claim 32 comprising defining the start of atrial tachycardia, and delivering said ATP sequence and said asynchronous pulses in timed relation to said start.

35. The method as described in claim 34, comprising determining if a suitable temporary pacing interval can be used, and if not waiting for a next atrial beat and then calculating said temporary pacing interval.

36. A system of cardiac pacing of a patient, comprising:

AT means for detecting the presence of AT;

ATP means for delivering an ATP sequence of atrial pulses to the patient'"'"'s atrium in response to detected AT;

ventricular pacing means for pacing the patient'"'"'s ventricle;

rate criteria means for limiting the rate of ventricular pacing; and

control means for controlling said ventricular pacing means to deliver ventricular pace pulses during said ATP sequence and for a next ventricular pace pulse after the end of said sequence at a rate that meets said rate criteria and provides that said next ventricular pace pulse is in cardiac synchrony with the last atrial pulse of said sequence

wherein said control means comprises AV means for storing predetermined AV criteria including values of AV max and AV min and calculating means for calculating a temporary pacing interval that meets said rate criteria and said AV criteria and also provides that said next ventricular pace pulse is delivered following said last atrial pace pulse by an AV interval that is no less than AV min and no more than AV max.