Apparatus for the nasal or oral delivery of a medicament
First Claim
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1. An apparatus for the nasal or oral delivery of a medicament to a patient, comprising:
- (a) a sealed flexible container including the medicament and a gaseous propellant for the medicament; and
(b) a delivery device, including;
(i) a main body part which, at least in use, holds the sealed flexible container, the main body part including a nozzle by which the medicament is delivered to the patient; and
(ii) a compressive part which, when actuated in use, compresses the sealed flexible container, thereby pressurizing the gaseous propellant within the container, which pressurization of the gaseous propellant causes to sealed flexible container to be ruptured and the propellant to expel the medicament from the apparatus, thereby delivering the medicament to the patient;
wherein the main body part includes a protrusion adjacent to the nozzle, to assist the rupturing of the sealed flexible container, the protrusion being arranged such that the compression of the sealed flexible container by the compressive part causes the sealed flexible container to be driven against the protrusion and thereby to be ruptured where it meets the protrusion.
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Abstract
An apparatus (1) for the nasal or oral delivery of a medicament, comprises: (a) a sealed flexible container (3) containing the medicament and a gaseous propellant for the medicament; and (b) a delivery device (5), comprising: (i) a main body part (5a) which, at least in use, holds the sealed flexible container (3); and (ii) a compressive part (5b) which, when actuated in use, causes the sealed flexible container (3) to be ruptured and the propellant to expel the medicament from the container, thereby delivering the medicament.
58 Citations
34 Claims
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1. An apparatus for the nasal or oral delivery of a medicament to a patient, comprising:
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(a) a sealed flexible container including the medicament and a gaseous propellant for the medicament; and (b) a delivery device, including; (i) a main body part which, at least in use, holds the sealed flexible container, the main body part including a nozzle by which the medicament is delivered to the patient; and (ii) a compressive part which, when actuated in use, compresses the sealed flexible container, thereby pressurizing the gaseous propellant within the container, which pressurization of the gaseous propellant causes to sealed flexible container to be ruptured and the propellant to expel the medicament from the apparatus, thereby delivering the medicament to the patient; wherein the main body part includes a protrusion adjacent to the nozzle, to assist the rupturing of the sealed flexible container, the protrusion being arranged such that the compression of the sealed flexible container by the compressive part causes the sealed flexible container to be driven against the protrusion and thereby to be ruptured where it meets the protrusion. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
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18. A delivery device for the nasal or oral delivery of a medicament, comprising:
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(i) a main body part arranged to hold, in use, a sealed flexible container containing a medicament and a gaseous propellant for the medicament the main body part including a nozzle by which the medicament is delivered to the patient; and (ii) a compressive part arranged to cause, when actuated in use, a sealed flexible container held by the main body part to be ruptured and the propellant to expel the medicament from the container, thereby delivering the medicament, wherein each of the compressive part and the main body part include an interlockable member by which the compressive part may interlock with the main body part, wherein the interlockable members are arranged to undergo a two-stage interlocking action including a first stage and a second stage, wherein the first stage includes closure of the delivery device to hold the sealed flexible container, and wherein the second stage occurs upon actuation of the compressive part; and
wherein the main body part includes a protrusion adjacent to the nozzle, to assist the rupturing of the sealed flexible container, the protrusion being arranged such that the compression of the sealed flexible container by the compressive part causes the sealed flexible container to be driven against the protrusion and thereby to be ruptured where it meets the protrusion. - View Dependent Claims (19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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Specification