Combined treatment for cataract and glaucoma treatment

• US 7,163,543 B2
• Filed: 06/07/2002
• Issued: 01/16/2007
• Est. Priority Date: 11/08/2001
• Status: Active Grant

• Current Assignee: Glaukos Corporation
• Original Assignee: Glaukos Corporation
• Inventors: Smedley, Gregory T., Tu, Hosheng, Haffner, David, Niksch, Barbara, Burns, Thomas W.
• Primary Examiner(s): HO, UYEN T
• Application Number:
  US10/165,616
• Publication Number:
  US 20030088260A1
• Time in Patent Office: 1,684 Days
• Field of Search: 606/6, 606/107, 606/5, 604/8, 604/5, 604/28, 604/27, 604/22
• US Class Current: 606/107
• CPC Class Codes: A61F 9/0017 implantable in, or in contact with, the eye, e.g. ocular inserts
• CPC Class Codes: A61F 9/00781 Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment drainage implants in general A61M27/002
• CPC Class Codes: A61L 2300/602 Type of release, e.g. controlled, sustained, slow
• CPC Class Codes: A61L 2300/606 Coatings
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence

Abstract

A method is provided for treatment of cataract in combination with a glaucoma procedure while maintaining the intraocular pressure by permitting aqueous to flow out of an anterior chamber of the eye through a surgically stented pathway. A trabecular stent is adapted for implantation within the trabecular meshwork of an eye such that intraocular liquid flows controllably from the anterior chamber of the eye to Schlemm'"'"'s canal, bypassing the trabecular meshwork. Depending upon the specific treatment contemplated, pharmaceuticals may be utilized in conjunction with the trabecular stent enabling post-cataract healing processes.

Claims

1. A method, of performing surgery to lower intraocular pressure of an eye, comprising:

providing an opening into an anterior chamber of the eye;

inserting an instrument into the anterior chamber through said opening to perform a cataract extraction from the eye;

providing an ocular implant having an inflow portion in fluid communication with an outflow portion;

transporting the ocular implant from the opening through the anterior chamber of the eye to a fluid collection channel of the eye;

positioning the ocular implant such that the inflow portion of the ocular implant is positioned in the anterior chamber and the outflow portion of the ocular implant is positioned at the fluid collection channel; and

permitting aqueous humor to flow from the anterior chamber of the eye through the inflow portion of the ocular implant to the outflow portion of the ocular implant and into the fluid collection channel of the eye;

wherein the fluid collection channel is selected from the group consisting of Schlemm'"'"'s canal, an aqueous collector channel, and an episcleral vein of the eye.

2. A method, of performing a combined surgery on an eye, comprising:

providing an opening into an anterior chamber of the eye;

extracting a cataract from the eye through the opening;

providing an ocular implant having an inflow portion in fluid communication with an outflow portion of the ocular implant;

transporting the ocular implant from the opening through the anterior chamber of the eye to Schlemm'"'"'s canal of the eye;

positioning the ocular implant such that the inflow portion of the ocular implant is positioned in the anterior chamber and the outflow portion of the ocular implant is positioned in Schlemm'"'"'s canal; and

permitting aqueous humor to flow from the anterior chamber of the eye through the inflow portion of the ocular implant to the outflow portion of the ocular implant and into Schlemm'"'"'s canal of the eye.

3. A method, of performing surgery to lower intraocular pressure of an eye, comprising:

providing an opening into an anterior chamber of the eye;

inserting an instrument into the anterior chamber through said opening to perform a cataract extraction from the eye;

providing an ocular implant having an inflow portion in fluid communication with an outflow portion;

transporting the ocular implant through the anterior chamber of the eye to a fluid collection channel of the eye;

positioning the ocular implant such that the inflow portion of the ocular implant is positioned in the anterior chamber and the outflow portion of the ocular implant is positioned at the fluid collection channel; and

permitting aqueous humor to flow from the anterior chamber of the eye through the inflow portion of the ocular implant to the outflow portion of the ocular implant and into to fluid collection channel of the eye;

wherein the fluid collection channel is selected from the group consisting of Schlemm'"'"'s canal, an aqueous collector channel, and an episcleral vein of the eye.

4. The method of claim 3, wherein the cataract extraction from the eye is performed prior to positioning the ocular implant.

5. The method of claim 3, wherein positioning the ocular implant is performed prior to the cataract extraction.

6. The method of claim 3, wherein the cataract extraction comprises phacoemulsification of a lens of the eye.

7. The method of claim 3, wherein positioning the ocular implant is part of a surgery to treat glaucoma.

8. The method of claim 7, wherein the surgery to treat glaucoma comprises making an incision in a trabecular meshwork of the eye to provide outflow of the aqueous humor.

9. The method of claim 3, wherein said method further comprises closing said opening after said instrument has been removed from the anterior chamber.

10. The method of claim 3, wherein said instrument comprises an ultrasonic instrument.

11. The method of claim 3, wherein transporting the ocular implant comprises using a second instrument.

12. The method of claim 11, wherein said second instrument comprises an applicator.

13. A method, of performing a combined surgery on an eye, comprising:

providing an opening into an anterior chamber of the eye;

extracting a cataract from the eye through the opening;

providing an ocular implant having an inflow portion in fluid communication with an outflow portion of the ocular implant;

transporting the ocular implant through the anterior chamber of the eye to Schlemm'"'"'s canal of the eye;

positioning the ocular implant such that the inflow portion of the ocular implant is positioned in the anterior chamber and the outflow portion of the ocular implant is positioned in Schlemm'"'"'s canal; and

permitting aqueous humor to flow from the anterior chamber of the eye through the inflow portion of the ocular implant to the outflow portion of the ocular implant and into Schlemm'"'"'s canal of the eye.

14. The method of claim 13, wherein extracting the cataract is performed prior to positioning the ocular implant.

15. The method of claim 13, wherein positioning the ocular implant is performed prior to extracting the cataract.

16. The method of claim 13, wherein extracting the cataract comprises phacoemulsification of a lens of the eye.

17. The method of claim 13, wherein the combined surgery comprises lowering intraocular pressure of the eye.

18. The method of claim 17, wherein the lowering of intraocular pressure is a treatment for glaucoma.

19. The method of claim 13, wherein said method further comprises making an incision in trabecular meshwork of the eye for receiving said ocular implant.

20. The method of claim 13, wherein said ocular implant comprises a tube.

21. The method of claim 13, wherein said ocular implant comprises a cutting tip for making an incision in trabecular meshwork of the eye.

22. The method of claim 13, wherein extracting the cataract comprises using an ultrasonic instrument.

23. The method of claim 13, wherein transporting the ocular implant comprises using an applicator.

24. The method of claim 23, wherein said applicator comprises an actuator to release said ocular implant from said applicator.