Spray processing of porous medical devices
First Claim
1. A method of coating a medical device, comprising:
- providing a medical device;
providing a coating material;
applying the coating material to the medical device by cold spray thermal processing wherein powder particles are introduced into a high pressure gas where both the gas and particles enter a supersonic jet which is directed against the medical device forming a porous coating, and wherein the medical device is selected from the group consisting of a stent, guide wires, lead tips, catheters and markers;
wherein the porous coating is functionally graded; and
applying a drug to the porous coating on the medical device.
1 Assignment
0 Petitions
Accused Products
Abstract
Thermal spray processing and cold spray processing are utilized to manufacture porous starting materials (such as tube stock, wire and substrate sheets) from biocompatible metals, metal alloys, ceramics and polymers that may be further processed into porous medical devices, such as stents. The spray processes are also used to form porous coatings on consolidated biocompatible medical devices. The porous substrates and coatings may be used as a reservoir to hold a drug or therapeutic agent for elution in the body. The spray-formed porous substrates and coatings may be functionally graded to allow direct control of drug elution without an additional polymer topcoat. The spray processes are also used to apply the drug or agent to the porous substrate or coating when drug or agent is robust enough to withstand the temperatures and velocities of the spray process with minimal degradation.
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Citations
16 Claims
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1. A method of coating a medical device, comprising:
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providing a medical device; providing a coating material; applying the coating material to the medical device by cold spray thermal processing wherein powder particles are introduced into a high pressure gas where both the gas and particles enter a supersonic jet which is directed against the medical device forming a porous coating, and wherein the medical device is selected from the group consisting of a stent, guide wires, lead tips, catheters and markers; wherein the porous coating is functionally graded; and applying a drug to the porous coating on the medical device. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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15. A method of coating a medical device, comprising:
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providing a medical device; providing a coating material; applying the coating material to the medical device by cold spray thermal processing wherein powder particles are introduced into a high pressure gas where both the gas and particles enter a supersonic jet which is directed against the medical device forming a porous coating, and wherein the medical device is selected from the group consisting of a stent, guide wires, lead tips, catheters and markers; applying a drug to the porous coating on the medical device; and wherein the porous coating is functionally graded with different degrees of porosity and/or density that allows the coating to function as a diffusion barrier to control the release of the drug. - View Dependent Claims (16)
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Specification