Therapeutic system

• US 7,164,940 B2
• Filed: 06/28/2001
• Issued: 01/16/2007
• Est. Priority Date: 03/25/1998
• Status: Expired due to Fees

• Current Assignee: Olympus Optical Company Ltd. (Olympus Corporation)
• Original Assignee: Olympus Optical Company Ltd. (Olympus Corporation)
• Inventors: Nagase, Toru, Hatta, Shinji, Hareyama, Norihiko
• Primary Examiner(s): Manuel; George
• Assistant Examiner(s): Jung; William C.
• Application Number:
  US09/894,697
• Publication Number:
  US 20010044575A1
• Time in Patent Office: 2,028 Days
• Field of Search: 600/427, 600437-472, 601 2- 4, 602/2, 606/27
• US Class Current: 600/427
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2090/374 NMR or MRI
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 2090/3954 magnetic, e.g. NMR or MRI
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/704 Tables
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 90/10 for stereotaxic surgery, e.g. frame-based stereotaxis
• CPC Class Codes: A61B 90/11 with guides for needles or instruments, e.g. arcuate slides or ball joints

Abstract

A therapeutic system comprising a therapeutic applicator for treating living tissues and an observation unit for determining the position of the applicator. The therapeutic energy applied from the applicator to the living tissues is controlled in accordance with data representing the position of the applicator, determined by the observation unit. It is therefore easy to operate the system even if the applicator and the observation unit (e.g., an MRI apparatus) are used at the same time. The image of the living tissues remains clear during the use of the therapeutic applicator.

Claims

1. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the setting section sets the at least one of the plurality of reference points and the at least one measuring line based on the tomogram data acquired by the data acquisition device.

2. A therapeutic system according to claim 1, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

3. A therapeutic system according to claim 1, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

4. A therapeutic system according to claim 1, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

5. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserter in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit uses, as tomogram data values, absolute values of luminances at the at least one of the plurality of reference points and the at least one measuring line.

6. A therapeutic system according to claim 5, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

7. A therapeutic system according to claim 5, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

8. A therapeutic system according to claim 5, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

9. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit uses, as tomogram data values, relative values of luminances at the at least one of the plurality of reference points and the at least one measuring line.

10. A therapeutic system according to claim 9, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

11. A therapeutic system according to claim 9, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

12. A therapeutic system according to claim 9, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

13. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion end a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit uses, as tomogram data values, differences between luminances measured at the at least one of the plurality of reference points and the at least one measuring line before the energy is applied and luminances measured at the at least one of the plurality of reference points and the at least one measuring line when the energy is applied.

14. A therapeutic system according to claim 13, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

15. A therapeutic system according to claim 13, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

16. A therapeutic system according to claim 13, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

17. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit uses, as tomogram data values, luminance-change rates measured at the at least one of the plurality of reference points and the at least one measuring line.

18. A therapeutic system according to claim 17, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

19. A therapeutic system according to claim 17, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

20. A therapeutic system according to claim 17, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

21. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit determines that tomogram data values at all of the at least one of the plurality of reference points and the at least one measuring line have reached respective threshold values.

22. A therapeutic system according to claim 21, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

23. A therapeutic system according to claim 21, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

24. A therapeutic system according to claim 21, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

25. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit sets the plurality of the reference points in the tomogram and determines that tomogram data values at all of the reference points have reached respective threshold values set for the reference points.

26. A therapeutic system according to claim 25, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

27. A therapeutic system according to claim 25, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

28. A therapeutic system according to claim 25, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

29. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit;

sets a first group of the reference points and a second group of the reference points in the tomogram,

determines whether tomogram data values at the reference points have reached respective threshold values,

determines and indicates that tomogram data values at the reference points of the first group have reached the threshold values, and

one of (i) inhibits the energy generating means from generating the energy or (ii) decreases the energy generated by the energy generating means when it is determined that image data values at the reference points of the second group have reached the threshold values.

30. A therapeutic system according to claim 29, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

31. A therapeutic system according to claim 29, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

32. A therapeutic system according to claim 29, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

33. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit uses, as tomogram data values, luminance-change rates measured at the measuring points.

34. A therapeutic system according to claim 33, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

35. A therapeutic system according to claim 33, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

36. A therapeutic system according to claim 33, wherein the tomogram data is acquired by supplying, to the affected from that of the energy source.

37. A therapeutic system comprising:

an energy source which generates energy to treat an internal affected region;

an applicator having a distal end portion and a proximal end portion and including a longitudinal member, wherein at least the distal end portion of the applicator is inserted in a living body and arranged at a position such that the affected region is enabled to be treated by the energy, and the energy is supplied to the affected region through the distal end portion of the applicator;

a data acquisition device to acquire tomogram data of the living body including the affected region;

a display to display a tomogram of living tissues including the affected region based on the tomogram data;

a setting section to set at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region; and

an observation unit including the display and the setting section, wherein the observation unit is adapted to observe a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region;

wherein the observation unit sets the reference points by setting a measuring line and distances from the measuring reference line.

38. A therapeutic system according to claim 37, wherein the observation unit one of (i) inhibits the energy generating means from generating the energy and (ii) decreases the energy generated by the energy generating means.

39. A therapeutic system according to claim 37, wherein the observation unit has manual setting means for setting the at least one of the plurality of reference points and the at least one measuring line when manually operated.

40. A therapeutic system according to claim 37, wherein the tomogram data is acquired by supplying, to the affected region, energy that is generated on a principle different from that of the energy source.

41. A method for a therapeutic system, the method comprising:

inserting a distal end portion of an applicator into a living body, wherein the applicator comprises the distal end portion and a proximal end portion and includes a longitudinal member, and the distal end portion of the applicator is adapted to emit energy to treat an affected region in the living body;

arranging at least the distal end portion of the applicator at a position such that the affected region is enabled to be treated by the energy;

supplying the energy to treat the affected region through the distal end portion of the applicator to the affected region;

acquiring tomogram data of the living body including the affected region;

displaying, on a display, a tomogram of the living body including the affected region based on the tomogram data,

setting at least one of a plurality of reference points and at least one measuring line on the tomogram displayed on the display before the energy is supplied to the affected region;

acquiring tomogram data of the living body including the affected region, when the applicator is inserted in the living body and the energy is supplied to the affected region; and

observing a condition of the affected region treated by the energy based on a change of the tomogram data corresponding to the at least one of the plurality of reference points and the at least one measuring line which varies as the energy is supplied to the affected region.