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Handheld apparatus and method for transdermal drug delivery and analyte extraction

  • US 7,164,942 B2
  • Filed: 02/09/2004
  • Issued: 01/16/2007
  • Est. Priority Date: 11/09/1998
  • Status: Expired due to Fees
First Claim
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1. A device for ablating stratum corneum epidermidis of skin on the body of a subject, comprising:

  • a plurality of electrodes, which are adapted to be applied to the skin of the subject at respective points; and

    a power source, which is adapted to apply electrical energy between two or more of the plurality of electrodes, to cause ablation of an area of the stratum corneum during a first time period, so as to facilitate passage of a substance through the ablated area into the body during a second time period, subsequent to the first time period,wherein the power source is adapted to apply the electrical energy as alternating current,wherein the plurality of electrodes comprise a common electrode and a plurality of positive electrodes, andwherein the power source is configured such that, during a phase of the alternating current, the alternating current from the power source flows from each positive electrode, through the skin, to the common electrode.

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