Vessel evaluation methods, apparatus, computer-readable media and signals

• US 7,165,010 B2
• Filed: 03/10/2003
• Issued: 01/16/2007
• Est. Priority Date: 03/08/2002
• Status: Expired due to Fees

• Current Assignee: University of British Columbia
• Original Assignee: University of British Columbia
• Inventors: Ryomoto, Arnold Kaoru, Mancini, Giovanni Battista
• Primary Examiner(s): Tsai; Carol S. W.
• Application Number:
  US10/383,574
• Publication Number:
  US 20030171894A1
• Time in Patent Office: 1,408 Days
• Field of Search: 702/182, 702/183, 600504-506, 600/513, 600/454
• US Class Current: 702/182
• CPC Class Codes: A61B 5/02007 Evaluating blood vessel condition, e.g. elasticity, compliance
• CPC Class Codes: A61B 5/1075 for measuring dimensions by non-invasive methods, e.g. for determining thickness of tissue layer A61B8/0858 takes precedence
• CPC Class Codes: A61B 6/481 involving the use of contrast agents
• CPC Class Codes: A61B 6/504 for diagnosis of blood vessels, e.g. by angiography
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 40/63 for local operation
• CPC Class Codes: G16H 70/60 relating to pathologies

Abstract

Methods, apparatuses, media and signals for evaluating a vessel. One method includes receiving at least one measurement of a physical dimension of the vessel, and producing an indication of abnormality in the vessel, in response to the at least one received measurement and at least one population-based parameter for the vessel. Producing may include producing an indication of stenosis of the vessel, in response to the physical dimension measurement and a population-based reference dimension for the vessel. This may include producing a population-based percent stenosis value in response to a ratio of the physical dimension measurement to the population-based reference dimension. Producing may further include identifying a shape characteristic of the vessel, which may include producing a tapering comparison value in response to the tapering of the vessel and a population-based average tapering value. The vessel may include a coronary artery segment, for example.

Claims

1. An apparatus for evaluating a vessel, the apparatus comprising:

a processor circuit configured to receive at least one measurement of a physical dimension of the vessel;

wherein the processor circuit is configured to produce an indication of abnormality in the vessel, in response to the at least one received measurement and at least one population-based reference physical dimension for the vessel.

2. The apparatus of claim 1 wherein the processor circuit is configured to produce, as the indication of abnormality, an indication of stenosis of the vessel, in response to the physical dimension measurement and the population-based reference physical dimension for the vessel.

3. The apparatus of claim 2 wherein the processor circuit is configured to produce, as the indication of stenosis, a population-based percent stenosis value, in response to a ratio of the physical dimension measurement to the population-based reference physical dimension.

4. The apparatus of claim 1 wherein the processor circuit is configured to produce, as the indication of abnormality, a comparison value relating the physical dimension measurement, the population-based reference physical dimension for the vessel, and an error value associated with the population-based reference physical dimension.

5. The apparatus of claim 1 wherein the processor circuit is configured to produce a Z-score in response to the physical dimension measurement, a population-based average reference dimension and an error value associated therewith.

6. The apparatus of claim 1 wherein the processor circuit is configured to identify a shape characteristic of the vessel.

7. The apparatus of claim 6 wherein the processor circuit is configured to receive first and second physical dimension measurements of the vessel, and wherein the processor circuit is configured to produce a tapering comparison value in response to a tapering of the vessel identified in response to the first and second physical dimension measurements, and a population-based average tapering value produced in response to the population-based reference physical dimension.

8. The apparatus of claim 1 further comprising an output device in communication with the processor circuit, and wherein the processor circuit is configured to control the output device to notify a user as to whether the indication indicates presence or absence of an apparent abnormality of the vessel.

9. The apparatus of claim 1 further comprising a storage medium in communication with the processor circuit for storing the at least one population-based reference physical dimension for the vessel.

10. An apparatus for evaluating a vessel, the apparatus comprising:

means for receiving at least one measurement of a physical dimension of the vessel;

means for producing an indication of abnormality in the vessel, in response to the at least one received measurement and at least one population-based reference physical dimension for the vessel.

11. A method of evaluating a vessel, the method comprising:

receiving at least one measurement of a physical dimension of the vessel;

producing an indication of abnormality in the vessel, in response to the at least one received measurement and at least one population-based reference physical dimension for the vessel.

12. The method of claim 11 wherein producing comprises producing an indication of stenosis of the vessel, in response to the physical dimension measurement and the population-based reference physical dimension for the vessel.

13. The method of claim 12 wherein producing an indication of stenosis comprises producing a population-based percent stenosis value, in response to a ratio of the physical dimension measurement to the population-based reference physical dimension.

14. The method of claim 11 wherein producing comprises producing a comparison value relating the physical dimension measurement, the population-based reference physical dimension for the vessel, and an error value associated with the population-based reference dimension.

15. The method of claim 11 wherein producing comprises producing a Z-score in response to the physical dimension measurement, a population-based average reference dimension and an error value associated therewith.

16. The method of claim 11 wherein producing comprises identifying a shape characteristic of the vessel.

17. The method of claim 16 wherein receiving comprises receiving first and second physical dimension measurements of the vessel, and wherein identifying the shape characteristic comprises producing a tapering comparison value in response to a tapering of the vessel identified in response to the first and second physical dimension measurements, and a population-based average tapering value produced in response to the population-based reference physical dimension.

18. The method of claim 11 further comprising notifying a user as to whether the indication indicates presence or absence of an apparent abnormality of the vessel.

19. The method of claim 11 further comprising storing the at least one population-based reference physical dimension for the vessel.

20. A computer-readable medium embodying codes for directing a processor circuit to carry out the method of claim 11.

21. A signal embodied in at least one of a communications medium and a carrier wave, the signal comprising code segments for directing a processor circuit to carry out the method of claim 11.

22. The method of claim 11 wherein the population-based reference physical dimension comprises a population-based geometrical reference dimension.

23. The method of claim 22 wherein the population-based reference physical dimension comprises a population-based reference diameter for the vessel.

24. The method of claim 22 wherein the population-based reference physical dimension comprises a population-based reference area for the vessel.