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Methods, compositions, and automated systems for separating rare cells from fluid samples

  • US 7,166,443 B2
  • Filed: 11/04/2003
  • Issued: 01/23/2007
  • Est. Priority Date: 10/11/2001
  • Status: Expired due to Term
First Claim
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1. An automated system for enriching rare cells of a fluid sample, comprising:

  • a) automated fluid volume sensing means for sensing the volume of at least one sample or a portion thereof provided in at least one tube or vessel, said automated fluid volume sensing means comprising at least one collated light source and at least one light-sensor;

    b) at least one filtration chamber that comprises or engages at least one microfabricated filter comprising one or more tapered pores;

    c) at least one power supply or signal source or control circuit for automated control and powering of fluid flow through said at least one filtration chamber; and

    d) means for collecting enriched rare cells.

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